FORTIMICIN-C, FORTIMICIN-D AND FORTIMICIN-KE NEW AMINOGLYCOSIDE ANTIBIOTICS

被引：21

作者：

SUGIMOTO, M ^{[1
]}

ISHII, S ^{[1
]}

OKACHI, R ^{[1
]}

NARA, T ^{[1
]}

机构：

[1] KYOWA HAKKO KOGYO CO LTD,TOKYO RES LAB,3-6-6 ASAHIMACHI,MACHIDASHI,TOKYO,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1979年 / 32卷 / 09期

关键词：

D O I：

10.7164/antibiotics.32.868

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

From the fermentation broth of Micromonospora olivoasterospora CS-26 that produced fortimicins A and B three new aminoglycoside antibiotics, fortimicins C, D and KE, were isolated. Fortimicins C and D exhibited potent, broad spectrum antibacterial activities against Gram-positive and negative bacteria, while fortimicin KE was only weakly active. © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：868 / 873

页数：6

共 9 条

[1] FORTIMICINS-A AND FORTIMICINS-B, NEW AMINOGLYCOSIDE ANTIBIOTICS .3. STRUCTURAL IDENTIFICATION [J].

EGAN, RS ;

STANASZEK, RS ;

CIROVIC, M ;

MUELLER, SL ;

TADANIER, J ;

MARTIN, JR ;

COLLUM, P ;

GOLDSTEIN, AW ;

DEVAULT, RL ;

SINCLAIR, AC ;

FAGER, EE ;

MITSCHER, LA .

JOURNAL OF ANTIBIOTICS, 1977, 30 (07) :552-563

[2] FORTIMICINS-A AND FORTIMICINS-B, NEW AMINOGLYCOSIDE ANTIBIOTICS .4. INVITRO STUDY OF FORTIMICIN A COMPARED WITH OTHER AMINOGLYCOSIDES [J].

GIROLAMI, RL ;

STAMM, JM .

JOURNAL OF ANTIBIOTICS, 1977, 30 (07) :564-570

[3] FORTIMICINS-A AND FORTIMICINS-B, NEW AMINOGLYCOSIDE ANTIBIOTICS .1. PRODUCING ORGANISM, FERMENTATION AND BIOLOGICAL PROPERTIES OF FORTIMICINS [J].

NARA, T ;

YAMAMOTO, M ;

KAWAMOTO, I ;

TAKAYAMA, K ;

OKACHI, R ;

TAKASAWA, S ;

SATO, T ;

SATO, S .

JOURNAL OF ANTIBIOTICS, 1977, 30 (07) :533-540

[4]

NARA T, 1978, ANNUAL REPORTS FERME, V2, P223

[5]

NARA T, 1977, ANN REP FERMENT P, V1, P299

[6] FORTIMICINS-A AND FORTIMICINS-B, NEW AMINOGLYCOSIDE ANTIBIOTICS .2. ISOLATION, PHYSICOCHEMICAL AND CHROMATOGRAPHIC PROPERTIES [J].

OKACHI, R ;

TAKASAWA, S ;

SATO, T ;

SATO, S ;

YAMAMOTO, M ;

KAWAMOTO, I ;

NARA, T .

JOURNAL OF ANTIBIOTICS, 1977, 30 (07) :541-551

[7] ENZYMATIC ACETYLATION OF FORTIMICIN-A AND SELDOMYCIN FACTOR-5 BY AMINOGLYCOSIDE 3-ACETYLTRANSFERASE I - [AAC(3)-I] OF ESCHERICHIA-COLI KY8348 [J].

SATO, S ;

IIDA, T ;

OKACHI, R ;

SHIRAHATA, K ;

NARA, T .

JOURNAL OF ANTIBIOTICS, 1977, 30 (11) :1025-1027

[8]

Tilley B. C, 1975, 31 M SOC IND MICR

[9] FORTIMICIN A PRODUCTION BY MICROMONOSPORA-OLIVOASTEROSPORA IN A CHEMICALLY DEFINED MEDIUM [J].

YAMAMOTO, M ;

OKACHI, R ;

KAWAMOTO, I ;

NARA, T .

JOURNAL OF ANTIBIOTICS, 1977, 30 (12) :1064-1072

← 1 →