Cherubism in sub-Saharan Africa: a first case-report in a child

被引:2
作者
Aloni, Michel Ntetani [1 ]
Kambere, Renault Sitwaminya [2 ]
Molua, Antoine [3 ]
Dilu, Joseph Nzinga [4 ]
Tshibassu, Pierre Manianga [5 ]
Kazadi-Lukusa, Aime [1 ]
Ngiyulu, Rene Makuala [1 ]
Kalengayi, Raphael Mbona [2 ]
Ehungu, Jean Lambert Gini [1 ]
机构
[1] Univ Kinshasa, Sch Med, Univ Hosp Kinshasa, Div Pediat Hematooncol & Nephrol,Dept Pediat, Kinshasa XI, DEM REP CONGO
[2] Univ Kinshasa, Sch Med, Univ Hosp Kinshasa, Dept Pathol, Kinshasa XI, DEM REP CONGO
[3] Univ Kinshasa, Sch Med, Univ Hosp Kinshasa, Dept Radiol, Kinshasa XI, DEM REP CONGO
[4] Univ Kinshasa, Sch Med, Univ Hosp Kinshasa, Dept Stomatol & Maxillofacial Surg, Kinshasa XI, DEM REP CONGO
[5] Univ Kinshasa, Sch Med, Univ Hosp Kinshasa, Div Gastroenterol & Neurol,Dept Pediat, Kinshasa XI, DEM REP CONGO
关键词
cherubism; jaw involvement; child; Kinshasa; Democratic Republic of Congo;
D O I
10.4081/rt.2015.5675
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Cherubism is rare disease and has been rarely reported in African pediatric population. We report here the case of a 10-year-old child who was referred to our hospital for bilateral jaws swelling. Physical examination revealed bilateral swelling symmetry of the face. Histopathological examination of the biopsy specimen showed loose fibrous stroma, proliferating fibrous connective with tissue interspersed with multinucleated giant cells, small thin walled blood vessels and scattered sparse mononuclear inflammatory infiltrate. Our patient presented cherubism. Cherubism is rarely described in children living in sub-Saharan Africa. Genetic and molecular investigations plays an important role in diagnosis but were not available in poor resources settings in developing countries such as the Democratic Republic of Congo.
引用
收藏
页码:11 / 13
页数:3
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