AN EFFICIENT ROUTE TO C-4 LINKED IMIDAZOLE NUCLEOSIDES - SYNTHESIS OF 2-CARBAMOYL-4-(2'-DEOXY-BETA-D-RIBOFURANOSYL)IMIDAZOLE

被引：24
|
作者：
BERGSTROM, DE [1 ]
ZHANG, PM [1 ]
机构：
[1] WALTHER CANC INST,INDIANAPOLIS,IN 46208
来源：
TETRAHEDRON LETTERS | 1991年 / 32卷 / 45期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/0040-4039(91)80199-G
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first synthesis of an imidazole C-nucleoside linked through C-4, 2-carbamoyl-4-(2'-deoxy-beta-D-ribofuranosyl) imidazole was achieved by way of a nine-step sequence starting from 2-deoxy-3, 5-di-O-p-toluoyl-D-erythro-pentofuranosyl chloride.
引用
收藏
页码：6485 / 6488
页数：4
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