PROCAINE INTERACTIONS WITH PHOSPHOLIPID MONOLAYERS AT THE AIR-WATER-INTERFACE

被引：0

作者：

ZSAKO, J

TOMOAIACOTISEL, M

CHIFU, E

MOCANU, A

FRANGOPOL, PT

机构：

[1] UNIV CLUJ NAPOCA,DEPT PHYS CHEM,R-3400 CLUJ NAPOCA,ROMANIA

[2] INST PHYS & NUCL ENGN,MAGURELE,ROMANIA

来源：

GAZZETTA CHIMICA ITALIANA | 1994年 / 124卷 / 01期

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Compressional isotherms of L-alpha-distearoylphosphatidylcholine (DSPC) monolayers spread on an aqueous subphase containing various concentrations of procaine (PR) have been recorded. The influence of PR upon the surface characteristics of DSPC monolayers is studied using the surface thermodynamics methods. Therefore, the PR adsorption values and penetration/binding numbers are derived from the compressional isotherms by means of Gibbs' equation. Results are compared with those obtained in the case of stearic acid and L-alpha-dipalmitoylphosphatidylcholine monolayers. Differences are discussed in terms of the molecular structure and hydrophobic interactions.

引用

页码：5 / 9

页数：5

共 35 条

[1]

ASGHARIAN B, UNPUB LANGMUIR

[2]

BOGGS JM, 1976, MOL PHARMACOL, V12, P136

[3] THE INTERACTION OF D-PROPRANOLOL AND DIMYRISTOYL PHOSPHATIDYLCHOLINE LARGE UNILAMELLAR VESICLES INVESTIGATED BY QUASI-ELASTIC LIGHT-SCATTERING AND FOURIER-TRANSFORM INFRARED-SPECTROSCOPY [J].