ISOLATION AND CHARACTERIZATION OF DNA FROM ARCHAEOLOGICAL BONE

被引：160

作者：

HAGELBERG, E

CLEGG, JB

机构：

来源：

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES | 1991年 / 244卷 / 1309期

关键词：

D O I：

10.1098/rspb.1991.0049

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

DNA was extracted from human and animal bones recovered from archaeological sites and mitochondrial DNA sequences were amplified from the extracts using the polymerase chain reaction. Evidence is presented that the amplified sequences are authentic and do not represent contamination by extraneous DNA. The results show that significant amounts of genetic information can survive for long periods in bone, and have important implications for evolutionary genetics, anthropology and forensic science.

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页码：45 / 50

页数：6

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