US Family Physicians Overestimate Personal omega-3 Fatty Acid Biomarker Status: Associations with Fatty Fish and omega-3 Supplement Intake

被引:5
作者
Matusheski, Nathan, V [1 ]
Marshall, Keri [2 ]
Hartunian-Sowa, Sonia [1 ]
McBurney, Michael, I [1 ]
机构
[1] North Amer Nutr Sci & Advocacy, DSM Nutr Prod, Parsippany, NJ 07045 USA
[2] Global Lipids Nutr Sci & Advocacy, DSM Nutr Prod, Columbia, MD USA
来源
CURRENT DEVELOPMENTS IN NUTRITION | 2018年 / 2卷 / 02期
关键词
omega-3; status; physicians; eicosapentaenoic acid; EPA; docosahexaenoic acid; DHA; fatty fish intake; omega-3 supplement use;
D O I
10.3945/cdn.117.002188
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Background: The health benefits of omega-3 (n-3) fatty acids are well established. Only a small percentage of Americans consume the recommended amounts of fatty fish, the main dietary source of omega-3 fatty acids, and most have low omega-3 fatty acid blood concentrations. Objective: We aimed to measure biomarkers of long-chain omega-3 fatty acid (EPA and DHA) status among family physicians, and determine whether having their omega-3 status tested would influence attitudes and patient recommendations. Methods: Family physicians attending a medical conference (n = 340) completed an omega-3 intake survey and had a finger stick blood sample taken. omega-3 Index, percentage of omega-6 (% n-6) in highly unsaturated fatty acids (HUFAs), and EPA: arachidonic acid (AA) ratio were calculated from whole blood fatty acid profiles. Post-conference, a subsample of participants (n = 100) responded to a survey regarding attitudes and recommendations about omega-3s. Results: Average age (mean +/- SEM) of participants was 48.0 +/- 0.7 y and 59% were women. Average omega-3 Index was 5.2% +/- 0.1%, % n-6 in HUFA was 75% +/- 0.4%, and EPA: AA ratio was 0.076 +/- 0.004. 57% of family physicians reported consuming < 2 servings/wk of fatty fish, and 78% reported using omega-3 supplements <= 1/wk. Although 51% believed omega-3 status was in a desirable range, only 5% had an omega-3 Index >= 8%. Biomarkers of omega-3 status were significantly associated with fatty fish intake and supplement use, and were correlated (R-2 ranging from 0.59 to 0.77). Physicians who had omega-3 status tested (n = 65) were more likely to agree with statements affirming the health benefits of omega-3 fatty acids and more willing to recommend omega-3 fatty acids to their patients (P = 0.004). Conclusions: Blood concentrations of omega-3 fatty acids in family physicians were below recommendations, and were associated with fatty fish intake and omega-3 supplement use. There was a discrepancy between perceived and actual omega-3 status. Increased awareness of personal omega-3 status among physicians may facilitate patient communication and recommendations about omega-3 fatty acid intake.
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页数:8
相关论文
共 45 条
[1]  
Adams KM, 2015, J BIOMED ED, V2015, P1, DOI [10.1155/2015/357627, DOI 10.1155/2015/357627]
[2]   A Meta-Analysis of Randomized Controlled Trials and Prospective Cohort Studies of Eicosapentaenoic and Docosahexaenoic Long-Chain Omega-3 Fatty Acids and Coronary Heart Disease Risk [J].
Alexander, Dominik D. ;
Miller, Paige E. ;
Van Elswyk, Mary E. ;
Kuratko, Connye N. ;
Bylsma, Lauren C. .
MAYO CLINIC PROCEEDINGS, 2017, 92 (01) :15-29
[3]   Quantitative Erythrocyte Omega-3 EPA Plus DHA Levels are Related to Higher Regional Cerebral Blood Flow on Brain SPECT [J].
Amen, Daniel G. ;
Harris, William S. ;
Kidd, Parris M. ;
Meysami, Somayeh ;
Raji, Cyrus A. .
JOURNAL OF ALZHEIMERS DISEASE, 2017, 58 (04) :1189-1199
[5]   Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes [J].
Bischoff-Ferrari, Heike A. ;
Giovannucci, Edward ;
Willett, Walter C. ;
Dietrich, Thomas ;
Dawson-Hughes, Bess .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2006, 84 (01) :18-28
[6]   Conversion of α-linolenic acid to longer-chain polyunsaturated fatty acids in human adults [J].
Burdge, GC ;
Calder, PC .
REPRODUCTION NUTRITION DEVELOPMENT, 2005, 45 (05) :581-597
[7]   ω-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease Pooling Project of 19 Cohort Studies [J].
Del Gobbo, Liana C. ;
Imamura, Fumiaki ;
Aslibekyan, Stella ;
Marklund, Matti ;
Virtanen, Jyrki K. ;
Wennberg, Maria ;
Yakoob, Mohammad Y. ;
Chiuve, Stephanie E. ;
dela Cruz, Luicito ;
Frazier-Wood, Alexis C. ;
Fretts, Amanda M. ;
Guallar, Eliseo ;
Matsumoto, Chisa ;
Prem, Kiesha ;
Tanaka, Tosh ;
Wu, Jason H. Y. ;
Zhou, Xia ;
Helmer, Catherine ;
Ingelsson, Erik ;
Yuan, Jian-Min ;
Barberger-Gateau, Pascale ;
Campos, Hannia ;
Chaves, Paulo H. M. ;
Djousse, Luc ;
Giles, Graham G. ;
Gomez-Aracena, Jose ;
Hodge, Allison M. ;
Hu, Frank B. ;
Jansson, Jan-Hakan ;
Johansson, Ingegerd ;
Khaw, Kay-Tee ;
Koh, Woon-Puay ;
Lemaitre, Rozenn N. ;
Lind, Lars ;
Luben, Robert N. ;
Rimm, Eric B. ;
Riserus, Ulf ;
Samieri, Cecilia ;
Franks, Paul W. ;
Siscovick, David S. ;
Stampfer, Meir ;
Steffen, Lyn M. ;
Steffen, Brian T. ;
Tsai, Michael Y. ;
van Dam, Rob M. ;
Voutilainen, Sari ;
Willett, Walter C. ;
Woodward, Mark ;
Mozaffarian, Dariush .
JAMA INTERNAL MEDICINE, 2016, 176 (08) :1155-1166
[8]  
Eckel R. H., 2014, Circulation, V129, pS76, DOI [10.1016/j.jacc.2013.11.003, 10.1161/01.cir.0000437740.48606.d1]
[9]  
EFSA, 2010, EFSA J, V8, P1796, DOI DOI 10.2903/J.EFSA.2010.1796
[10]  
FAO WHO, 2011, REP JOINT FAO WHO EX