HIGHER-ORDER NUCLEOPROTEIN COMPLEXES IN TRANSCRIPTION - ANALOGIES WITH SITE-SPECIFIC RECOMBINATION

被引：146
作者：
GROSSCHEDL, R [1 ]
机构：
[1] UNIV CALIF SAN FRANCISCO, HOWARD HUGHES MED INST, DEPT BIOCHEM, SAN FRANCISCO, CA 94143 USA
来源：
CURRENT OPINION IN CELL BIOLOGY | 1995年 / 7卷 / 03期
关键词：
D O I：
10.1016/0955-0674(95)80091-3
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Regulation of transcription involves the assembly of multiprotein complexes at enhancers and promoters. interactions between adjacent and non-adjacent DNA-binding proteins can augment the specificity and stability of multicomponent nucleoprotein complexes. Recently, several proteins have been identified that can function as 'architectural' elements in the assembly of higher-order nucleoprotein structures reminiscent of those involved in site-specific recombination in prokaryotes.
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页码：362 / 370
页数：9
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