EVIDENCE FOR THE SECRETION OF INHIBIN-LIKE IMMUNOREACTIVITY FROM CULTURED HUMAN ADRENAL-CELLS

被引：22

作者：

HAJI, M

NISHI, Y

TANAKA, S

OHASHI, M

SEKIYA, K

HASEGAWA, Y

IGARASHI, M

SASAMOTO, S

NAWATA, H

机构：

[1] GUNMA UNIV,SCH MED,DEPT OBSTET & GYNECOL,MAEBASHI,GUNMA 371,JAPAN

[2] TOKYO UNIV AGR & TECHNOL,VET PHYSIOL LAB,FUCHU,TOKYO 183,JAPAN

来源：

JOURNAL OF ENDOCRINOLOGY | 1991年 / 128卷 / 03期

关键词：

D O I：

10.1677/joe.0.128R013

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We have studied the production and release of inhibin-like immunoreactivity in the human adrenal gland. Extract of human adrenal glands showed a displacement curve paralleled with the inhibin standard. Inhibin-like immunoreactivity contents in the adrenal gland was 1893 +/- 474 (mean +/- S.D.) IU/g wet weight tissue. ACTH stimulated the secretion of inhibin-like immunoreactivity as well as cortisol and aldosterone in a dose-dependent manner in the cultured adrenal cells. These results indicate that the human adrenal gland produces and secretes inhibin-like peptide in response to ACTH.

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页码：R13 / R16

页数：4

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