IDENTIFICATION OF PROSTAGLANDIN-E2 AND LEUKOTRIENE-B4 IN THE SYNOVIAL-FLUID OF PAINFUL, DYSFUNCTIONAL TEMPOROMANDIBULAR JOINTS

被引:153
作者
QUINN, JH
BAZAN, NG
机构
[1] LOUISIANA STATE UNIV,MED CTR,DEPT ORAL & MAXILLOFACIAL SURG,NEW ORLEANS,LA 70119
[2] LOUISIANA STATE UNIV,MED CTR,DEPT OPHTHALMOL,NEW ORLEANS,LA 70119
[3] LOUISIANA STATE UNIV,MED CTR,DEPT BIOCHEM & MOLEC BIOL,NEW ORLEANS,LA 70119
[4] LOUISIANA STATE UNIV,MED CTR,DEPT NEUROL,NEW ORLEANS,LA 70119
关键词
D O I
10.1016/0278-2391(90)90011-P
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
It has been hypothesized that prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) should be present in the synovial fluid of inflamed, dysfunctional temporomandibular joints. An assay to identify PGE2 and LTB4 and platelet-activating factor (PAF) was used, and a strong correlation between the levels of these lipid mediators of pain and inflammation and an index of clinical joint pathology was found. © 1990.
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页码:968 / 971
页数:4
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