How to stop: the mysterious links among RNA polymerase II occupancy 3 vertical bar of genes, mRNA 3 ' processing and termination

被引：12
作者：
Anamika, Krishanpal [1 ]
Gyenis, Akos [1 ]
Tora, Laszlo [1 ]
机构：
[1] Univ Strasbourg, IGBMC, CNRS UMR 7104, INSERM,U964, Illkirch Graffenstaden, France
来源：
TRANSCRIPTION-AUSTIN | 2013年 / 4卷 / 01期
关键词：
genome-wide mapping; RNA Polymerase II pause; core histone genes; End of Annotated Gene; polyadenylation; transcription termination; R-loops;
D O I：
10.4161/trns.22300
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Eukaryotic genes are transcribed by RNA polymerase II (RNAP II) through cycles of initiation, elongation and termination. Termination remains the least understood stage of transcription. Here we discuss the role of RNAP II occupancy downstream of the 3' ends of genes and its links with termination and mRNA 3' processing.
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页码：7 / 12
页数：6
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