THE HUMAN GENE ENCODING THE LARGEST SUBUNIT OF RNA-POLYMERASE-II

被引：15
|
作者：
MITA, K
TSUJI, H
MORIMYO, M
TAKAHASHI, E
NENOI, M
ICHIMURA, S
YAMAUCHI, M
HONGO, E
HAYASHI, A
机构：
[1] NATL INST RADIOL SCI, DIV GENET, INAGE KU, CHIBA 263, JAPAN
[2] OTSUKA PHARMACEUT CO LTD, Kawaguchi, TOKUSHIMA 77101, JAPAN
[3] NATL INST RADIOL SCI, SCH TRAINING, INAGE KU, CHIBA 263, JAPAN
来源：
GENE | 1995年 / 159卷 / 02期
关键词：
NUCLEOTIDE SEQUENCING; RPII; GENE STRUCTURE;
D O I：
10.1016/0378-1119(95)00081-G
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The nucleotide sequence of a large portion of the human RNA polymerase II large subunit (RpII LS)-encoding gene and its whole gene structure were determined, The RpIILS gene consists of 29 exons. The sequence of the 5' flanking region is highly conserved as compared with that of the mouse RpIILS and contains several SP1-binding sites, a CCAAT sequence and a sequence homologous to a heat-shock element, In addition, several inverted repeats and palindrome sequences were involved in the 5' upstream region, Those suggest that the 5' flanking domain of RpIILS would be highly structured which may be responsible for transcriptional regulation.
引用
收藏
页码：285 / 286
页数：2
相关论文
共 50 条
  • [1] ANALYSIS OF THE GENE ENCODING THE LARGEST SUBUNIT OF RNA POLYMERASE-II IN DROSOPHILA
    JOKERST, RS
    WEEKS, JR
    ZEHRING, WA
    GREENLEAF, AL
    MOLECULAR & GENERAL GENETICS, 1989, 215 (02): : 266 - 275
  • [2] CHROMOSOMAL ASSIGNMENT OF GENE ENCODING THE LARGEST SUBUNIT OF RNA POLYMERASE-II IN THE MOUSE
    PRAVTCHEVA, D
    RABIN, M
    BARTOLOMEI, M
    CORDEN, J
    RUDDLE, FH
    SOMATIC CELL AND MOLECULAR GENETICS, 1986, 12 (05) : 523 - 528
  • [3] CHROMOSOMAL LOCALIZATION OF HUMAN RNA-POLYMERASE-II SUBUNIT GENES
    ACKER, J
    MATTEI, MG
    WINTZERITH, M
    ROECKEL, N
    DEPETRIS, D
    VIGNERON, M
    KEDINGER, C
    GENOMICS, 1994, 20 (03) : 496 - 499
  • [4] THE GENE ENCODING THE LARGE SUBUNIT OF HUMAN RNA POLYMERASE-II
    CHO, KWY
    KHALILI, K
    ZANDOMENI, R
    WEINMANN, R
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1985, 260 (28) : 5204 - 5210
  • [5] A HUMAN CDNA-ENCODING THE SMALL-SUBUNIT OF RNA-POLYMERASE-II TRANSCRIPTION FACTOR SIII
    GARRETT, KP
    HAQUE, D
    CONAWAY, RC
    CONAWAY, JW
    GENE, 1994, 150 (02) : 413 - 414
  • [6] Genetic variation in RPOIILS gene encoding RNA polymerase II largest subunit from Leishmania major
    Eslami, Gilda
    Salehi, Rasoul
    MOLECULAR BIOLOGY REPORTS, 2014, 41 (04) : 2585 - 2589
  • [7] Genetic variation in RPOIILS gene encoding RNA polymerase II largest subunit from Leishmania major
    Gilda Eslami
    Rasoul Salehi
    Molecular Biology Reports, 2014, 41 : 2585 - 2589
  • [8] STRUCTURE OF THE GENE ENCODING THE 14.5 KDA SUBUNIT OF HUMAN RNA POLYMERASE-II
    ACKER, J
    WINTZERITH, M
    VIGNERON, M
    KEDINGER, C
    NUCLEIC ACIDS RESEARCH, 1993, 21 (23) : 5345 - 5350
  • [9] COMPLETE SEQUENCE OF THE HUMAN RNA POLYMERASE-II LARGEST SUBUNIT
    WINTZERITH, M
    ACKER, J
    VICAIRE, S
    VIGNERON, M
    KEDINGER, C
    NUCLEIC ACIDS RESEARCH, 1992, 20 (04) : 910 - 910
  • [10] ANALYSIS OF THE GENES ENCODING THE LARGEST SUBUNIT OF RNA POLYMERASE-II IN ARABIDOPSIS AND SOYBEAN
    DIETRICH, MA
    PRENGER, JP
    GUILFOYLE, TJ
    PLANT MOLECULAR BIOLOGY, 1990, 15 (02) : 207 - 223
12345