EFFECT OF LONG-TERM ANGIOTENSIN-CONVERTING ENZYME-INHIBITION ON VASCULAR FUNCTION IN PATIENTS WITH CHRONIC CONGESTIVE-HEART-FAILURE

被引：36

作者：

JESERICH, M ^{[1
]}

PAPE, L ^{[1
]}

JUST, H ^{[1
]}

HORNIG, B ^{[1
]}

KUPFER, M ^{[1
]}

MUNZEL, T ^{[1
]}

LOHMANN, A ^{[1
]}

OLSCHEWSKI, M ^{[1
]}

DREXLER, H ^{[1
]}

机构：

[1] UNIV MASSACHUSETTS,MED CTR,DIV CARDIOL,WORCESTER,MA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1995年 / 76卷 / 14期

关键词：

D O I：

10.1016/S0002-9149(99)80305-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We demonstrate that peripheral vasodilatory capacity is impaired in patients with chronic congestive heart failure not treated with aspirin, but preserved in patients taking aspirin. Chronic angiotensin-converting enzyme inhibition improves the decreased vasodilatory capacity in these patients, indicating that locally acting cyclooxygenase-dependent factors contribute to peripheral vasoconstriction in chronic congestive heart failure.

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页码：1079 / &

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