STRATUM-CORNEUM SPHINGOLIPIDS AND FREE AMINO-ACIDS IN EXPERIMENTALLY-INDUCED SCALY SKIN

被引：42

作者：

DENDA, M ^{[1
]}

HORI, J ^{[1
]}

KOYAMA, J ^{[1
]}

YOSHIDA, S ^{[1
]}

NANBA, R ^{[1
]}

TAKAHASHI, M ^{[1
]}

HORII, I ^{[1
]}

YAMAMOTO, A ^{[1
]}

机构：

[1] NIIGATA UNIV, SCH MED, DEPT DERMATOL, NIIGATA 951, JAPAN

来源：

ARCHIVES OF DERMATOLOGICAL RESEARCH | 1992年 / 284卷 / 06期

关键词：

SPHINGOLIPIDS; CERAMIDE; SCALY SKIN; AMINO ACIDS;

D O I：

10.1007/BF00372041

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Stratum corneum sphingolipids are of particular importance in maintaining the water permeability barrier of mammalian epidermis. Free amino acids also play an important role in water retention in the stratum corneum. To clarify the way in which these substances affect scaly skin, stratum corneum sphingolipids and free amino acids collected from artificially-induced scaly skin were analysed. Scaly skin was induced by tape stripping. The total amount of sphingolipids was quantified by gas chromatography and five of sphingolipid fractions were isolated and quantified by thin-layer chromatography. Free amino acids were analysed using a high-speed amino analyser. The total amount of sphingolipid in scaly skin did not differ statistically from that in control skin. However, a significant change in the distribution of the five sphingolipid species was observed in scaly skin and the total amount of amino acids was decreased in scaly skin. These results suggest that the distribution of these five types of sphingolipid and the total amount of amino acids are responsible for scaly skin.

引用

页码：363 / 367

页数：5

共 50 条

[41] CHANGES IN INDIVIDUAL PLASMA AMINO-ACIDS FOLLOWING EXPERIMENTALLY INDUCED SAND FLY FEVER VIRUS-INFECTION
WANNEMACHER, RW
VOLLMER, RT
BARTELLONI, PJ
BEISEL, WR
PEKAREK, RS
METABOLISM-CLINICAL AND EXPERIMENTAL, 1972, 21 (01): : 67 - +
[42] URINARY FREE AMINO-ACID EXCRETION AS A MEASURE OF ALTERATIONS IN PROTEIN-METABOLISM DURING EXPERIMENTALLY-INDUCED INFECTIONS IN MAN
WANNEMACHER, RW
DINTERMAN, RE
PEKAREK, RS
BEISEL, WR
FEDERATION PROCEEDINGS, 1974, 33 (03) : 669 - 669
[43] FILTRATION-INDUCED RELEASE OF DISSOLVED FREE AMINO-ACIDS - APPLICATION TO CULTURES OF MARINE PROTOZOA
NAGATA, T
KIRCHMAN, DL
MARINE ECOLOGY PROGRESS SERIES, 1990, 68 (1-2) : 1 - 5
[44] SALINITY INDUCED ACCUMULATION OF FREE AMINO-ACIDS IN GERMINATING RICE SEEDS DIFFERING IN SALT TOLERANCE
DUBEY, RS
RANI, M
JOURNAL OF AGRONOMY AND CROP SCIENCE, 1989, 163 (04) : 236 - 247
[45] DISTRIBUTION OF FREE AMINO-ACIDS IN STREPTOZOTOCIN-INDUCED DIABETIC PREGNANT RATS, THEIR PLACENTAE AND FETUSES
COPELAND, AD
HENDRICH, CE
PORTERFIELD, SP
HORMONE AND METABOLIC RESEARCH, 1990, 22 (02) : 65 - 70
[46] DESTABILIZATION OF WHOLE SKIN LIPID BIO-LIPOSOMES INDUCED BY SKIN PENETRATION ENHANCERS AND FT-IR ATR (FOURIER-TRANSFORM INFRARED ATTENUATED TOTAL REFLECTION) ANALYSIS OF STRATUM-CORNEUM LIPIDS
TAKEUCHI, Y
YASUKAWA, H
YAMAOKA, Y
MORIMOTO, Y
NAKAO, S
FUKUMORI, Y
FUKUDA, T
CHEMICAL & PHARMACEUTICAL BULLETIN, 1992, 40 (02) : 484 - 487
[47] RESPECTIVE ROLES OF AMMONIA, AMINO-ACIDS, AND MEDIUM-SIZED MOLECULES IN THE PATHOGENESIS OF EXPERIMENTALLY INDUCED ACUTE HEPATIC-ENCEPHALOPATHY
DENIS, J
DELORME, ML
BOSCHAT, M
NORDLINGER, B
OPOLON, P
JOURNAL OF NEUROCHEMISTRY, 1983, 40 (01) : 10 - 19
[48] DAMAGE OF AMINO-ACIDS AND PROTEINS INDUCED BY NITROGEN-DIOXIDE, A FREE-RADICAL TOXIN, IN AIR
KIKUGAWA, K
KATO, T
OKAMOTO, Y
FREE RADICAL BIOLOGY AND MEDICINE, 1994, 16 (03) : 373 - 382
[49] MEDIUM-INDUCED CHANGES IN PATTERNS OF FREE AND COMBINED AMINO-ACIDS IN MYCELIUM OF SERPULA-LACRIMANS
VENABLES, CE
WATKINSON, SC
MYCOLOGICAL RESEARCH, 1989, 92 : 273 - 277
[50] LITHIUM-INDUCED CHANGES IN THE BRAIN LEVELS OF FREE AMINO-ACIDS IN STRESS-EXPOSED RATS
EROGLU, L
BINYILDIZ, P
ATAMERSIMSEK, S
PSYCHOPHARMACOLOGY, 1980, 70 (02) : 187 - 189

← 1 2 3 4 5 →