EFFECTS OF COLD AND MELATONIN ON THE MICROTUBULES OF THE TOAD SCIATIC-NERVE

被引：15

作者：

PIEZZI, RS ^{[1
]}

CAVICCHIA, JC ^{[1
]}

机构：

[1] UNIV NACL CUYO, FAC CIENCIAS MED, INST HISTOL & EMBRIOL, MENDOZA, ARGENTINA

来源：

ANATOMICAL RECORD | 1981年 / 200卷 / 01期

关键词：

D O I：

10.1002/ar.1092000111

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

The effects of melatonin and cooling on the disintegration and reassembly of microtubules were studied in the sciatic nerve of the toad. Control and melatonin-treated nerves showed disintegration of the majority of microtubules after 2 h of cooling. When room temperature was restored, microtubules were reformed in the controls, but not in the nerves treated by melatonin where the disorganization persisted. Melatonin interferes with the microtubular reassembly after cooling of the axons of the sciatic nerve.

引用

页码：115 / 120

页数：6

共 32 条

[1] REGIONAL UPTAKE OF 3H-MELATONIN FROM BLOOD OR CEREBROSPINAL FLUID BY RAT BRAIN [J].

ANTONTAY, F ;

WURTMAN, RJ .

NATURE, 1969, 221 (5179) :474-&

[2] BRAIN SEROTONIN CONCENTRATION - ELEVATION FOLLOWING INTRAPERITONEAL ADMINISTRATION OF MELATONIN [J].

ANTONTAY, F ;

CHOU, C ;

ANTON, S ;

WURTMAN, RJ .

SCIENCE, 1968, 162 (3850) :277-+

[3]

ANTONTAY F, 1971, PINEAL GLAND, P213

[4] MITOTIC ARREST BY MELATONIN [J].

BANERJEE, S ;

MARGULIS, L .

EXPERIMENTAL CELL RESEARCH, 1973, 78 (02) :314-318

[5] MELATONIN - INHIBITION OF MICROTUBULE-BASED ORAL MORPHOGENESIS IN STENTOR-COERULEUS [J].

BANERJEE, S ;

WINSTON, M ;

KERR, V ;

KELLEHER, JK ;

MARGULIS, L .

JOURNAL OF PROTOZOOLOGY, 1972, 19 (01) :108-&

[6] LOCALIZATION OF MELATONIN IN NERVOUS SYSTEM [J].

BARCHAS, JD ;

LERNER, AB .

JOURNAL OF NEUROCHEMISTRY, 1964, 11 (06) :489-&

[7] INCOMPLETE MICROTUBULES OBSERVED IN MAMMALIAN BLOOD PLATELETS DURING MICROTUBULE POLYMERIZATION [J].

BEHNKE, O .

JOURNAL OF CELL BIOLOGY, 1967, 34 (02) :697-&

[8] EFFECT OF MITOTIC INHIBITORS ON MYOGENESIS IN VITRO [J].

BISCHOFF, R ;

HOLTZER, H .

JOURNAL OF CELL BIOLOGY, 1968, 36 (01) :111-+

[9] MELATONIN EFFECTS ON BRAIN - INTERACTION WITH MICROTUBULE PROTEIN, INHIBITION OF FAST AXOPLASMIC FLOW AND INDUCTION OF CRYSTALLOID AND TUBULAR FORMATIONS IN HYPOTHALAMUS [J].

CARDINALI, DP ;

FREIRE, F .

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1975, 2 (05) :317-330

[10] UPTAKE AND EFFECTS OF MELATONIN ON SYNTHESIS OF PROTEINS BY RAT CEREBRAL-CORTEX [J].

CARDINALI, DP ;

NAGLE, CA ;

ROSNER, JM .

LIFE SCIENCES, 1973, 13 (07) :823-833

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