EFFECT OF AZTREONAM UPON HUMAN POLYMORPHONUCLEAR LEUKOCYTE FUNCTIONS

被引：1
|
作者：
RODRIGUEZ, AB
SANCHEZ, C
BARRIGA, C
机构：
来源：
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES | 1992年 / 15卷 / 02期
关键词：
HUMAN NEUTROPHILS; AZTREONAM; CHEMOTAXIS; PHAGOCYTOSIS;
D O I：
10.1016/0147-9571(92)90112-5
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Aztreonam (SQ 26,776), a new synthetic monobactam with an excellent antibacterial spectrum was analyzed in vitro. In this paper, the effect of aztreonam on the phagocytic process of human neutrophils isolated from fifteen healthy volunteers was studied. Chemotaxis was not modified with aztreonam at any of the doses used (10, 20, 40, 60, 80 and 100-mu-g/ml). On the other hand, this antibiotic at 100-mu-g/ml significantly increases (P < 0.05) Candida albicans ingestion as well as their digestion by neutrophils at 10 and 100-mu-g/ml.
引用
收藏
页码：131 / 136
页数：6
相关论文
共 50 条
  • [1] Effect of antituberculous drugs on human polymorphonuclear leukocyte functions in vitro
    Okuyan, B
    Izzettin, FV
    Sancar, M
    Ertas, Ö
    Çevikbas, A
    Gürer, US
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2005, 5 (7-8) : 1337 - 1342
  • [2] LACK OF STIMULATING EFFECT OF ISOPRINOSINE ON HUMAN POLYMORPHONUCLEAR LEUKOCYTE FUNCTIONS INVITRO
    CORBERAND, J
    LAHARRAGUE, P
    NGUYEN, F
    FONTANILLES, AM
    GLEIZES, B
    GYRARD, E
    INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY, 1980, 2 (02): : 145 - 149
  • [3] INHIBITION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTE FUNCTIONS BY IBUPROFEN
    NIELSEN, VG
    WEBSTER, RO
    IMMUNOPHARMACOLOGY, 1987, 13 (01): : 61 - 71
  • [4] Effect of antipyretics on polymorphonuclear leukocyte functions in children
    Gürer, ÜS
    Palanduz, A
    Gürbüz, B
    Yildirmak, Y
    Çevikbas, A
    Kayaalp, N
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2002, 2 (11) : 1599 - 1602
  • [5] EFFECT OF PIRPROFEN ON POLYMORPHONUCLEAR LEUKOCYTE FUNCTIONS INVITRO
    CAPSONI, F
    VENEGONI, E
    MINONZIO, F
    ONGARI, AM
    MARESCA, V
    ZANUSSI, C
    INTERNATIONAL JOURNAL OF TISSUE REACTIONS-EXPERIMENTAL AND CLINICAL ASPECTS, 1987, 9 (06): : 465 - 470
  • [6] The effect of taurine on polymorphonuclear leukocyte functions in endotoxemia
    H. Erdamar
    N. Türközkan
    M. Ekremoğlu
    Y. Kurt
    H. Yaman
    Amino Acids, 2007, 33 : 581 - 585
  • [7] The effect of taurine on polymorphonuclear leukocyte functions in endotoxemia
    Erdamar, H.
    Tuerkoezkan, N.
    Ekremoglu, M.
    Kurt, Y.
    Yaman, H.
    AMINO ACIDS, 2007, 33 (04) : 581 - 585
  • [8] In vitro effects of clarithromycin on human polymorphonuclear leukocyte functions
    Kadir, T
    Izzetin, FV
    Çevikbas, A
    Johansson, CB
    Clark, P
    CHEMOTHERAPY, 2000, 46 (03) : 198 - 203
  • [9] PREGNANCY SERUM EFFECTS ON HUMAN POLYMORPHONUCLEAR LEUKOCYTE FUNCTIONS
    PERSELLIN, RH
    RUSHING, JK
    JOURNAL OF CLINICAL INVESTIGATION, 1974, 53 (06): : A59 - A59
  • [10] Effect of montelukast on polymorphonuclear leukocyte functions in asthmatic patients
    Gürer, ÜS
    Büyüköztürk, S
    Palandüz, S
    Gürbüz, B
    Çevikbas, A
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2003, 3 (09) : 1257 - 1260
12345