METACHROMATIC CELLS IN NASAL-MUCOSA AFTER ALLERGEN CHALLENGE

被引：24
|
作者：
BORRES, MP
IRANDER, K
BJORKSTEN, B
机构：
[1] LINKOPING UNIV, FAC HLTH SCI, DEPT PEDIAT, S-58185 LINKOPING, SWEDEN
[2] LINKOPING UNIV, FAC HLTH SCI, DEPT OTORHINOLARYNGOL, S-58185 LINKOPING, SWEDEN
来源：
ALLERGY | 1990年 / 45卷 / 02期
关键词：
allergen challenge; metachromatic cells; nasal mucosa;
D O I：
10.1111/j.1398-9995.1990.tb00465.x
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Metachromatic cells in the nasal mucosa were studied in relation to symptoms in 16 schoolchildren and 11 adults with hay fever who were challenged with pollen outside the pollen season, using either a gentle scraping‐cytocentrifugation method for collection of mucosal specimens or biopsies. There was a temporary redistribution of metachromatic cells towards the mucosal surface appearing 5–24 h after challenge, with a correlation between the quantity of metachromatic cells and symptom scores. Thus, a single exposure to high doses of allergen may contribute to priming in susceptible individuals. Copyright © 1990, Wiley Blackwell. All rights reserved
引用
收藏
页码：98 / 103
页数：6
相关论文
共 50 条
  • [41] Nasal challenge with allergen leads to maxillary sinus inflammation
    Baroody, Fuad M.
    Mucha, Samantha M.
    De Tineo, Marcy
    Naclerio, Robert M.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2008, 121 (05) : 1126 - 1132
  • [42] DISTRIBUTION OF GALANIN-IMMUNOREACTIVE NERVE-FIBERS IN THE RAT NASAL-MUCOSA
    MATSUDA, Y
    INAGAKI, S
    NAKAI, Y
    TAKAGI, H
    BRAIN RESEARCH, 1990, 536 (1-2) : 344 - 346
  • [43] Allergen binding to specific IgE in the nasal mucosa of allergic patients
    KleinJan, A
    Godthelp, T
    vanToornenenbergen, AW
    Fokkens, WJ
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1997, 99 (04) : 515 - 521
  • [44] Eosinophils in bronchial mucosa of asthmatics after allergen challenge: effect of anti-IgE treatment
    van Rensen, E. L. J.
    Evertse, C. E.
    van Schadewijk, W. A. A. M.
    van Wijngaarden, S.
    Ayre, G.
    Mauad, T.
    Hiemstra, P. S.
    Sterk, P. J.
    Rabe, K. F.
    ALLERGY, 2009, 64 (01) : 72 - 80
  • [45] Reactivity of nasal cavity mucosa in the nasal cow's milk allergen provocation test
    Krzych-Falta, Edyta
    Wojas, Oksana
    Namyslowski, Andrzej
    Samolinski, Boleslaw
    Bialek, Stawomir
    Furmanczyk, Konrad
    POSTEPY DERMATOLOGII I ALERGOLOGII, 2023, 40 (01): : 87 - 92
  • [46] NITRIC-OXIDE SYNTHASE IN RAT NASAL-MUCOSA - IMMUNOHISTOCHEMICAL AND HISTOCHEMICAL-LOCALIZATION
    LEE, SH
    IWANAGA, T
    HOSHI, O
    ADACHI, I
    FUJITA, T
    ACTA OTO-LARYNGOLOGICA, 1995, 115 (06) : 823 - 829
  • [47] LOCALIZATION OF HISTAMINE N-METHYLTRANSFERASE MESSENGER-RNA IN HUMAN NASAL-MUCOSA
    OKAYAMA, M
    YAMAUCHI, K
    SEKIZAWA, K
    OKAYAMA, H
    SASAKI, H
    INAMURA, N
    MAEYAMA, K
    WATANABE, T
    TAKISHIMA, T
    SHIRATO, K
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1995, 95 (01) : 96 - 102
  • [48] DISTRIBUTION OF NADPH-DIAPHORASE POSITIVE NERVE-FIBERS IN THE RAT NASAL-MUCOSA
    HANAZAWA, T
    MOTOSUGI, H
    KONNO, A
    KANEKO, T
    TANAKA, K
    CHIBA, T
    NEUROSCIENCE LETTERS, 1993, 159 (1-2) : 71 - 74
  • [49] IN-VITRO PERMEATION OF SEVERAL MODEL-DRUGS ACROSS RABBIT NASAL-MUCOSA
    KUBO, H
    HOSOYA, K
    NATSUME, H
    SUGIBAYASHI, K
    MORIMOTO, Y
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1994, 103 (01) : 27 - 36
  • [50] RUTHENIUM RED ANTAGONISM OF CAPSAICIN-INDUCED VASCULAR CHANGES IN THE RAT NASAL-MUCOSA
    BARI, F
    JANCSO, G
    EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 1994, 251 (05) : 287 - 292
12345