METACHROMATIC CELLS IN NASAL-MUCOSA AFTER ALLERGEN CHALLENGE

被引：24
|
作者：
BORRES, MP
IRANDER, K
BJORKSTEN, B
机构：
[1] LINKOPING UNIV, FAC HLTH SCI, DEPT PEDIAT, S-58185 LINKOPING, SWEDEN
[2] LINKOPING UNIV, FAC HLTH SCI, DEPT OTORHINOLARYNGOL, S-58185 LINKOPING, SWEDEN
来源：
ALLERGY | 1990年 / 45卷 / 02期
关键词：
allergen challenge; metachromatic cells; nasal mucosa;
D O I：
10.1111/j.1398-9995.1990.tb00465.x
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Metachromatic cells in the nasal mucosa were studied in relation to symptoms in 16 schoolchildren and 11 adults with hay fever who were challenged with pollen outside the pollen season, using either a gentle scraping‐cytocentrifugation method for collection of mucosal specimens or biopsies. There was a temporary redistribution of metachromatic cells towards the mucosal surface appearing 5–24 h after challenge, with a correlation between the quantity of metachromatic cells and symptom scores. Thus, a single exposure to high doses of allergen may contribute to priming in susceptible individuals. Copyright © 1990, Wiley Blackwell. All rights reserved
引用
收藏
页码：98 / 103
页数：6
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