4 NEW AZAPHILONES FROM CHAETOMIUM-GLOBOSUM VAR FLAVO-VIRIDAE

被引：80

作者：

TAKAHASHI, M ^{[1
]}

KOYAMA, K ^{[1
]}

NATORI, S ^{[1
]}

机构：

[1] MEIJI COLL PHARM, YATO CHO TANASHISHI, TOKYO 188, JAPAN

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1990年 / 38卷 / 03期

关键词：

13C-NMR; azaphilone; biosynthesis; Chaetomium globosum var. flavo-viridae; chaetoviridin A; chaetoviridin B; chaetoviridin C; chaetoviridin D;

D O I：

10.1248/cpb.38.625

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Four new azaphilones of angular type, named chaetoviridins A, B, C and D, were isolated from the culture of Chaetomium globosum var. flavo-viridae. The absolute configuration of chaetoviridin A was established on the basis of the spectral data and chemical reactions. The structures of chaetoviridins B, C and D were suggested by the spectral data. The result of a biosynthetic study of chaetoviridin B from sodium [l,2-13C2\acetate gave support to the angular structure. © 1990, The Pharmaceutical Society of Japan. All rights reserved.

引用

页码：625 / 628

页数：4

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