VARIANT HUMAN PHOSPHORIBOSYLPYROPHOSPHATE SYNTHETASE ALTERED IN REGULATORY AND CATALYTIC FUNCTIONS

被引：84

作者：

BECKER, MA

RAIVIO, KO

BAKAY, B

ADAMS, WB

NYHAN, WL

机构：

[1] UNIV CALIF SAN DIEGO,DEPT MED,LA JOLLA,CA 92093

[2] UNIV CALIF SAN DIEGO,DEPT PEDIAT,LA JOLLA,CA 92093

来源：

JOURNAL OF CLINICAL INVESTIGATION | 1980年 / 65卷 / 01期

关键词：

D O I：

10.1172/JCI109640

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：109 / 120

页数：12

共 46 条

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[2] MECHANISM OF ALLOPURINOL-MEDIATED INCREASE IN ENZYME-ACTIVITY IN MAN
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[3] REGIONAL LOCALIZATION OF THE GENE FOR HUMAN PHOSPHORIBOSYLPYROPHOSPHATE SYNTHETASE ON THE X-CHROMOSOME
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YEN, RCK
ITKIN, P
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[4] GOUT WITH PURINE OVERPRODUCTION DUE TO INCREASED PHOSPHORIBOSYLPYROPHOSPHATE SYNTHETASE-ACTIVITY
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[J]. AMERICAN JOURNAL OF MEDICINE, 1973, 55 (02) : 232 - 242
[5] PATTERNS OF PHOSPHORIBOSYLPYROPHOSPHATE AND RIBOSE-5-PHOSPHATE CONCENTRATION AND GENERATION IN FIBROBLASTS FROM PATIENTS WITH GOUT AND PURINE OVERPRODUCTION
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[J]. JOURNAL OF CLINICAL INVESTIGATION, 1976, 57 (02) : 308 - 318
[6] BECKER MA, 1975, J BIOL CHEM, V250, P6822
[7] BECKER MA, 1977, J BIOL CHEM, V252, P3911
[8] HUMAN PHOSPHORIBOSYLPYROPHOSPHATE SYNTHETASE - INCREASED ENZYME SPECIFIC ACTIVITY IN A FAMILY WITH GOUT AND EXCESSIVE PURINE SYNTHESIS
BECKER, MA
KOSTEL, PJ
MEYER, LJ
SEEGMILLER, JE
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (10) : 2749 - 2752
[9] BECKER MA, 1978, URIC ACID, V51, P155
[10] EFFECTS OF NICOTINIC-ACID ON HUMAN FIBROBLAST PURINE BIOSYNTHESIS
BOYLE, JA
BECKER, MA
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[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1972, 269 (02) : 179 - +

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