MR Imaging-Guided Partial Volume Correction of PET Data in PET/MR Imaging

被引:34
作者
Erlandsson, Kjell [1 ]
Dickson, John [2 ]
Arridge, Simon [3 ]
Atkinson, David [4 ]
Ourselin, Sebastien [5 ]
Hutton, Brian F. [1 ,6 ]
机构
[1] UCLH, Univ Coll London, Inst Nucl Med, Euston Rd T-5, London NW1 2BU, England
[2] Univ Coll London Hosp, Inst Nucl Med, Euston Rd T-5, London NW1 2BU, England
[3] UCL, Dept Comp Sci, Gower St, London WC1E 6BT, England
[4] UCL, Ctr Med Imaging, 250 Euston Rd, London NW1 2PG, England
[5] UCL, Ctr Med Imaging Comp, Gower St, London WC1E 6BT, England
[6] Univ Wollongong, Ctr Med Radiat Phys, Northfields Ave, Wollongong, NSW 2522, Australia
基金
英国工程与自然科学研究理事会;
关键词
Partial volume effects; Partial volume correction; PET/MR imaging; Quantification;
D O I
10.1016/j.cpet.2015.09.002
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Partial volume effects are caused by the limited spatial resolution of the PET system. There is increasing evidence that partial volume correction (PVC) is necessary to guarantee quantitative accuracy in PET; however, there is reluctance to apply PVC routinely in clinical practice, partly because of uncertainty regarding the method of choice. To perform accurate PVC, it is necessary to introduce information from high-resolution anatomic images, such as MR imaging. All the methods rely on accurate coregistration between the anatomic image and the PET image. PET/MR imaging offers clear advantages for PVC and can help alleviate the image registration issues.
引用
收藏
页码:161 / +
页数:18
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