What is the Best Colonoscopy Surveillance for Lynch Syndrome Patients?

被引：0

作者：

Feau, Sandrine ^{[1
]}

Caulet, Morgane ^{[1
,2
]}

Lecomte, Thierry ^{[1
,2
]}

机构：

[1] CHRU Tours, Trousseau Univ Hosp, Dept Hepatogastroenterol & Digest Oncol, 2 Ave Republ, F-37044 Tours 09, France

[2] Univ Tours, Tours, France

来源：

CURRENT COLORECTAL CANCER REPORTS | 2016年 / 12卷 / 02期

关键词：

Lynch syndrome screening; Colonoscopy; Colorectal cancer; Virtual colonoscopy; Adenoma; Hereditary nonpolyposis colorectal cancer; Patient compliance; Autofluorescence endoscopy; Narrow band imaging; Chromoendoscopic colonoscopy; Surveillance; Interval cancer; Adenoma carcinoma; Sequence colorectal;

D O I：

10.1007/s11888-016-0314-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Lynch syndrome is the most common form of hereditary colorectal cancer. Screening programs have reduced colon cancer mortality. Despite intensive surveillance, the cumulative risk of developing colorectal cancer is substantial. Identification of modifiable factors has the potential to improve outcome of surveillance. Our article will review current guidelines for Lynch syndrome and how to perform colonoscopy. High-quality surveillance colonoscopy should be performed in an experimented center every 1-2 years, starting at the age of 20-25 years. Colonoscopy should include meticulous inspection and precise removal of all polyps, with special attention to the right colon especially of flat lesions. News endoscopic techniques, such as chromoendoscopy, were developed and recommended to improve the detection of adenomas, particularly of flat adenomas, and minimize the risk of developing interval cancer. Finally, educational intervention in a surveillance program is essential for optimizing screening including adherence.

引用

页码：88 / 93

页数：6

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