IRREVERSIBLE ENZYME INHIBITORS .78. INHIBITORS OF THYMIDINE PHOSPHORYLASE .4. HYDROPHOBIC BONDING BY URACILS SUBSTITUTED AT 5 AND 6 POSITIONS

被引：30

作者：

BAKER, BR

KAWAZU, M

机构：

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1967年 / 10卷 / 03期

关键词：

D O I：

10.1021/jm00315a004

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：311 / &

共 14 条

[1] STUDIES IN CHEMOTHERAPY .10. ANTITHYROID COMPOUNDS - SYNTHESIS OF 5-SUBSTITUTED AND 6-SUBSTITUTED 2-THIOURACILS FROM BETA-OXOESTERS AND THIOUREA [J].

ANDERSON, GW ;

HALVERSTADT, IF ;

MILLER, WH ;

ROBLIN, RO .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1945, 67 (12) :2197-2200

[2] IRREVERSIBLE ENZYME INHIBITORS .75. INHIBITORS OF THYMIDINE PHOSPHORTLASE .I. MODE OF RIBOFURANOSE BINDING [J].

BAKER, BR .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :297-&

[3] FACTORS IN DESIGN OF ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS [J].

BAKER, BR .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1964, 53 (04) :347-&

[4] IRREVERSIBLE ENZYME INHIBITORS .77. INHIBITORS OF THYMIDINE PHOSPHORYLASE .3. HYDROPHOBIC BONDING BY 1-SUBSTITUTED URACILS CONTAINING ADDITIONAL SUBSTITUENTS AT 5 AND 6 POSITIONS [J].

BAKER, BR ;

KAWAZU, M ;

SANTI, DV ;

SCHWAN, TJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :304-&

[5] IRREVERSIBLE ENZYME INHIBITORS .80. INHIBITORS OF THYMIDINE PHOSPHORYLASE .6. HYDROPHOBIC BONDING WITH 6 SUBSTITUENTS ON ACIDIC 5-NITRO- AND 5-BROMOURACILS [J].

BAKER, BR ;

KAWAZU, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :316-&

[6] IRREVERSIBLE ENZYME INHIBITORS .79. INHIBITORS OF THYMIDINE PHOSPHORYLASE .V. MODE OF PYRIMIDINE BINDING [J].

BAKER, BR ;

KAWAZU, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :313-&

[7] IRREVERSIBLE ENZYME INHIBITORS .76. INHIBITORS OF THYMIDINE PHOSPHORYLASE .2. HYDROPHOBIC BONDING BY 1-SUBSTITUTED URACILS [J].

BAKER, BR ;

KAWAZU, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :302-&

[8]

BAKER BR, 1967, DESIGN ACTIVESITE DI

[9]

BROWN DJ, 1952, J APPL CHEM, V2, P239

[10]

BROWN DJ, 1962, PYRIMIDINES, P472

← 1 2 →