ANTICONVULSANT ACTIVITY OF ARYL AND HETARYLSULFONYLHYDRAZONES

被引：0
|
作者：
DARIAS, V [1 ]
ABDALLAH, S [1 ]
DELGADO, L [1 ]
VEGA, S [1 ]
机构：
[1] CSIC,INST QUIM MED,E-28006 MADRID,SPAIN
来源：
PHARMAZIE | 1995年 / 50卷 / 11期
关键词：
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A series of aryl and hetarylsulfonylhydrazones of aromatic aldehydes were tested for acute toxicity and anticonvulsant activity in mice. Some of these compounds were effective in the MES, pentetrazol and strychnine tests. Thiophene derivatives were the most active terms of the series.
引用
收藏
页码：756 / 758
页数：3
相关论文
共 50 条
  • [1] Anticonvulsant semicarbazones: Are aryl groups necessary for activity?
    Dimmock, JR
    Vashishtha, SC
    Stables, JP
    PHARMAZIE, 1995, 50 (12): : 823 - 824
  • [2] Anticonvulsant activity of various aryl, arylidene and aryloxyaryl semicarbazones
    Puthucode, RN
    Pugazhenthi, U
    Quail, JW
    Stables, JP
    Dimmock, JR
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1998, 33 (7-8) : 595 - 607
  • [3] SYNTHESIS AND CYTOSTATIC ACTIVITY OF SOME ARYLSULFONYLHYDRAZONES AND HETARYLSULFONYLHYDRAZONES
    VEGA, S
    DIAZ, JA
    PHARMAZIE, 1992, 47 (10): : 765 - 767
  • [4] Synthesis and anticonvulsant activity of 4-aryl-2-hydroxytetronimides
    Olsen, Mark J.
    Clewett, Cathy
    Iacoban, Paulina
    Hubbard, Matthew
    Cox, Thomas
    Stables, James P.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [5] Synthesis and potential anticonvulsant activity of new aryl sulfonyl semicarbazide derivatives
    Nie, Yousong
    Zhong, Min
    Jiang, Zhiyuan
    Sun, Jian
    Guo, Yangguang
    Ding, Fei
    Li, Hang
    Zhang, Yongmin
    He, Xianran
    MEDICINAL CHEMISTRY RESEARCH, 2016, 25 (07) : 1425 - 1432
  • [6] Synthesis and anticonvulsant activity of halo-substituted aryl urea and thioureas
    Gupta, Mahesh Kumar
    Pandeya, Suerendra N.
    Zaiad, Golal M.
    Gangwar, V. S.
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2010, 87 (11) : 1421 - 1424
  • [7] Synthesis and anticonvulsant activity of 4-bromophenyl substituted aryl semicarbazones
    Pandeya, SN
    Yogeeswari, P
    Stables, JP
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2000, 35 (10) : 879 - 886
  • [8] Synthesis and potential anticonvulsant activity of new aryl sulfonyl semicarbazide derivatives
    Yousong Nie
    Min Zhong
    Zhiyuan Jiang
    Jian Sun
    Yangguang Gao
    Fei Ding
    Hang Li
    Yongmin Zhang
    Xianran He
    Medicinal Chemistry Research, 2016, 25 : 1425 - 1432
  • [9] SYNTHESIS AND ANTICONVULSANT ACTIVITY OF 1-ARYL-3-METHYLENE-2-PYRROLIDINONE ADDUCTS
    KORNET, MJ
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1985, 22 (01) : 129 - 130
  • [10] SYNTHESIS AND ANTICONVULSANT ACTIVITY OF 1-ARYL-5-AMIDO-1,2,3-TRIAZOLINES
    KADABA, PK
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1991, 201 : 130 - MEDI
12345