EFFECT OF ADMINISTRATION OF SERUM THYMIC-FACTOR (FTS) IN CALVES AND RABBITS INFECTED WITH BOVINE IMMUNODEFICIENCY-LIKE VIRUS

被引：9

作者：

HIRAI, N

FURUYAMA, H

AWAYA, A

ONUMA, M

机构：

[1] HOKKAIDO UNIV,FAC VET MED,DEPT EPIZOOTIOL,SAPPORO,HOKKAIDO 060,JAPAN

[2] RAKUNO GAKUEN UNIV,SCH VET MED,EBETSU,HOKKAIDO 069,JAPAN

[3] MITSUI PHARMACEUT INC,INST BIOL SCI,MOBARA,CHIBA 297,JAPAN

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 1995年 / 57卷 / 02期

关键词：

BOVINE IMMUNODEFICIENCY-LIKE VIRUS (BIV); IMMUNODEFICIENCY; LENTIVIRUS; SERUM THYMIC FACTOR (FTS);

D O I：

10.1292/jvms.57.307

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The effect of serum thymic factor (FTS) administration in bovine immunodeficiency-like virus (BIV)-infected calves and rabbits was examined. We previously found that some of the macrophage functions were depressed and humoral immune responses against foreign proteins were delayed in BIV-infected calves compared to uninfected calves. After FTS administration, however, no delay of antibody responses against foreign proteins was observed in BIV-infected calves. Though the chemiluminescence (CL) responses of macrophages in BIV-infected calves were significantly depressed (p<0.05), FTS administration resulted in the recovery of the CL responses in the BIV-infected calves comparable to those in the control calves. Antibody responses against foreign proteins in BIV-infected rabbits were significantly depressed (p<0.025) as compared with those in uninfected rabbits, though the depression became no significant after FTS administration.

引用

页码：307 / 310

页数：4