WATER-DEPRIVATION IN THE RAT INDUCES NITRIC-OXIDE SYNTHASE (NOS) GENE-EXPRESSION IN THE HYPOTHALAMIC PARAVENTRICULAR AND SUPRAOPTIC NUCLEI

被引：85

作者：

UETA, Y ^{[1
]}

LEVY, A ^{[1
]}

CHOWDREY, HS ^{[1
]}

LIGHTMAN, SL ^{[1
]}

机构：

[1] UNIV BRISTOL,BRISTOL ROYAL INFIRM,DEPT MED,BRISTOL BS2 8HW,AVON,ENGLAND

来源：

NEUROSCIENCE RESEARCH | 1995年 / 23卷 / 03期

关键词：

WATER DEPRIVATION; NITRIC OXIDE SYNTHASE; PARAVENTRICULAR NUCLEUS; SUPRAOPTIC NUCLEUS; SUBFORNICAL ORGAN; RAT;

D O I：

10.1016/0168-0102(95)00956-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We examined the effects of water deprivation on nitric oxide synthase (NOS) gene expression in the rat hypothalamic paraventricular (PVN) and supraoptic nuclei (SON), using in situ hybridization histochemistry. Dehydration caused a significant increase in NOS gene transcripts in the PVN and SON but not in the subfornical organ (SFO). The results suggest that dehydration has a major effect on the NOS gene expression in the PVN and SON.

引用

页码：317 / 319

页数：3

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