WATER-DEPRIVATION IN THE RAT INDUCES NITRIC-OXIDE SYNTHASE (NOS) GENE-EXPRESSION IN THE HYPOTHALAMIC PARAVENTRICULAR AND SUPRAOPTIC NUCLEI

被引：85
|
作者：
UETA, Y [1 ]
LEVY, A [1 ]
CHOWDREY, HS [1 ]
LIGHTMAN, SL [1 ]
机构：
[1] UNIV BRISTOL,BRISTOL ROYAL INFIRM,DEPT MED,BRISTOL BS2 8HW,AVON,ENGLAND
来源：
NEUROSCIENCE RESEARCH | 1995年 / 23卷 / 03期
关键词：
WATER DEPRIVATION; NITRIC OXIDE SYNTHASE; PARAVENTRICULAR NUCLEUS; SUPRAOPTIC NUCLEUS; SUBFORNICAL ORGAN; RAT;
D O I：
10.1016/0168-0102(95)00956-6
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
We examined the effects of water deprivation on nitric oxide synthase (NOS) gene expression in the rat hypothalamic paraventricular (PVN) and supraoptic nuclei (SON), using in situ hybridization histochemistry. Dehydration caused a significant increase in NOS gene transcripts in the PVN and SON but not in the subfornical organ (SFO). The results suggest that dehydration has a major effect on the NOS gene expression in the PVN and SON.
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页码：317 / 319
页数：3
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