WATER-DEPRIVATION IN THE RAT INDUCES NITRIC-OXIDE SYNTHASE (NOS) GENE-EXPRESSION IN THE HYPOTHALAMIC PARAVENTRICULAR AND SUPRAOPTIC NUCLEI

被引：85
|
作者：
UETA, Y [1 ]
LEVY, A [1 ]
CHOWDREY, HS [1 ]
LIGHTMAN, SL [1 ]
机构：
[1] UNIV BRISTOL,BRISTOL ROYAL INFIRM,DEPT MED,BRISTOL BS2 8HW,AVON,ENGLAND
来源：
NEUROSCIENCE RESEARCH | 1995年 / 23卷 / 03期
关键词：
WATER DEPRIVATION; NITRIC OXIDE SYNTHASE; PARAVENTRICULAR NUCLEUS; SUPRAOPTIC NUCLEUS; SUBFORNICAL ORGAN; RAT;
D O I：
10.1016/0168-0102(95)00956-6
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
We examined the effects of water deprivation on nitric oxide synthase (NOS) gene expression in the rat hypothalamic paraventricular (PVN) and supraoptic nuclei (SON), using in situ hybridization histochemistry. Dehydration caused a significant increase in NOS gene transcripts in the PVN and SON but not in the subfornical organ (SFO). The results suggest that dehydration has a major effect on the NOS gene expression in the PVN and SON.
引用
收藏
页码：317 / 319
页数：3
相关论文
共 50 条
  • [1] INHIBITION OF HYPOTHALAMIC NITRIC-OXIDE SYNTHASE GENE-EXPRESSION IN THE RAT PARAVENTRICULAR NUCLEUS BY FOOD-DEPRIVATION IS INDEPENDENT OF SEROTONIN DEPLETION
    UETA, Y
    LEVY, A
    CHOWDREY, HS
    LIGHTMAN, SL
    JOURNAL OF NEUROENDOCRINOLOGY, 1995, 7 (11) : 861 - 865
  • [2] Effect of suckling on NADPH-diaphorase (nitric oxide synthase, NOS) reactivity and NOS gene expression in the paraventricular and supraoptic nuclei of lactating rats
    Otukonyong, EE
    Okere, CO
    Johnstone, LE
    Murata, T
    Kaba, H
    Higuchi, T
    JOURNAL OF NEUROENDOCRINOLOGY, 2000, 12 (10) : 1001 - 1008
  • [3] Water-deprivation-induced expression of neuronal nitric oxide synthase in the hypothalamic paraventricular nucleus of rat
    Ryu, Vitaly
    Lee, Jong-Ho
    Um, Ji Won
    Yoo, Sang Bae
    Lee, Jisun
    Chung, Kwang Chul
    Jahng, Jeong Won
    JOURNAL OF NEUROSCIENCE RESEARCH, 2008, 86 (06) : 1371 - 1379
  • [4] Neuronal nitric oxide synthase in paraventricular and supraoptic hypothalamic nuclei of experimentally diabetic rats
    Salkovic-Petrisic, M
    Chapman, C
    Bicknell, RJ
    PERIODICUM BIOLOGORUM, 2002, 104 (01) : 67 - 72
  • [5] Hypovolemia upregulates the expression of neuronal nitric oxide synthase gene in the paraventricular and supraoptic nuclei of rats
    Ueta, Y
    Levy, A
    Lightman, SL
    Hara, Y
    Serino, R
    Nomura, M
    Shibuya, I
    Hattori, Y
    Yamashita, H
    BRAIN RESEARCH, 1998, 790 (1-2) : 25 - 32
  • [6] NITRIC-OXIDE SYNTHASE (NOS) GENE-EXPRESSION AFTER RETINAL ISCHEMIA IN RATS
    HANGAI, M
    YOSHIMURA, N
    MANDAI, M
    HONDA, Y
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1994, 35 (04) : 1608 - 1608
  • [7] HYPOTHALAMIC NITRIC-OXIDE SYNTHASE GENE-EXPRESSION IS REGULATED BY THYROID-HORMONES
    UETA, Y
    LEVY, A
    CHOWDREY, HS
    LIGHTMAN, SL
    ENDOCRINOLOGY, 1995, 136 (10) : 4182 - 4187
  • [8] Food or water deprivation modulate nitric oxide synthase (NOS) activity and gene expression in rat hypothalamic neurones: Correlation with neurosecretory activity?
    OShea, RD
    Gundlach, AL
    JOURNAL OF NEUROENDOCRINOLOGY, 1996, 8 (06) : 417 - 425
  • [9] Reproductive Regulation of Gene Expression in the Hypothalamic Supraoptic and Paraventricular Nuclei
    Augustine, R. A.
    Bouwer, G. T.
    Seymour, A. J.
    Grattan, D. R.
    Brown, C. H.
    JOURNAL OF NEUROENDOCRINOLOGY, 2016, 28 (04)
  • [10] THE EFFECT OF LACTATION ON NITRIC-OXIDE SYNTHASE GENE-EXPRESSION
    CECCATELLI, S
    ERIKSSON, M
    BRAIN RESEARCH, 1993, 625 (01) : 177 - 179
12345