SULFUR-CONTAINING AMIDES FROM GLYCOSMIS SPECIES WITH DIFFERENT ANTIFUNGAL ACTIVITY

被引:44
作者
GREGER, H [1 ]
ZECHNER, G [1 ]
HOFER, O [1 ]
HADACEK, F [1 ]
WURZ, G [1 ]
机构
[1] UNIV VIENNA,INST ORGAN CHEM,A-1090 VIENNA,AUSTRIA
关键词
GLYCOSMIS-MAURITIANA; G-PENTAPHYLLA; RUTACEAE; LEAVES; METHYLTHIOAMIDES; CINNAMIDES; CHEMOSYSTEMATICS; ANTIFUNGAL ACTIVITY;
D O I
10.1016/S0031-9422(00)90802-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Leaf extracts from different Sri Lankan provenances of Glycosmis mauritiana and G. pentaphlylla have been compared by HPLC analyses and tested for antifungal activity. All collections of G. pentaphylla are uniformly characterized by the known alkaloids arborine, skimmianine and arborinine, whereas the different provenances of G. mauritiana differ by displaying chemical polymorphism of different sulphur-containing amides. Three new amides, named illukumbin B, methylillukumbin B and methylillukumbin A, have been isolated and their structures are described on the basis of spectroscopic evidence. They show different antifungal activities in bioautographic tests and appear to be accumulated mainly in individuals collected from more humid and elevated habitats.
引用
收藏
页码:175 / 179
页数:5
相关论文
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