PRECLINICAL NEUROPHYSIOLOGICAL SIGNS OF PARKINSONISM IN OCCUPATIONAL MANGANESE EXPOSURE

被引:0
|
作者
WENNBERG, A
HAGMAN, M
JOHANSSON, L
机构
关键词
MANGANISM; NEUROPHYSIOLOGY; PARKINSONISM; SMELTING WORKS; STEEL INDUSTRY;
D O I
暂无
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
To study the effects from low level exposure to manganese, 30 men at steel smelting works and 60 nonexposed reference subjects, were neurophysiologically examined using: (i) Electroencephalogram (EEG), Event related auditory evoked potential (AEP/P300), Brain stem auditory evoked potential (BAEP) and diadochokinesometry. No group differences concerning EEG or BAEP were found. Diadochokinesis was slower and there was a tendency towards prolonged P300 latency in the exposed group as compared to the referents. These effects may be interpreted as early (subclinical) signs of disturbances of the same type as parkinsonism.
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页码:271 / 274
页数:4
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