CLONING AND NUCLEOTIDE-SEQUENCE OF THE FABD GENE ENCODING MALONYL COENZYME A-ACYL CARRIER PROTEIN TRANSACYLASE OF ESCHERICHIA-COLI

被引：36
作者：
MAGNUSON, K
OH, W
LARSON, TJ
CRONAN, JE
机构：
[1] UNIV ILLINOIS,DEPT MICROBIOL,131 BURRILL HALL,407 S GOODWIN AVE,URBANA,IL 61801
[2] UNIV ILLINOIS,DEPT BIOCHEM,URBANA,IL 61801
[3] VIRGINIA POLYTECH INST & STATE UNIV,DEPT BIOCHEM & NUTR,BLACKSBURG,VA 24061
来源：
FEBS LETTERS | 1992年 / 299卷 / 03期
关键词：
MALONYL TRANSACYLASE; MALONYL-COA; ACYL TRANSFERASE; FATTY ACID BIOSYNTHESIS;
D O I：
10.1016/0014-5793(92)80128-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We report the cloning and nucleotide sequence of the gene encoding malonyl coenzyme A-acyl carrier protein transacylase of Escherichia coli. Malonyl transacylase has been overexpressed 155-fold compared to a wild-type strain. Overexpression of this enzyme alters the fatty acid composition of a wild-type E. coli strain; increased amounts of cis-vaccenate are incorporated into the membrane phospholipids.
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页码：262 / 266
页数：5
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