Acute Watershed Infarcts with Global Cerebral Hypoperfusion in Symptomatic CADASIL

被引：7

作者：

Gordhan, Ajeet ^{[1
]}

Hudson, Brian K. ^{[2
]}

机构：

[1] St Joseph Med Ctr, Dept Neurointervent Radiol, 2200 East Washington Ave, Bloomington, IL 61701 USA

[2] Advocate Bromenn Med Ctr, Dept Neurosurg, Bloomington, IL USA

来源：

JOURNAL OF RADIOLOGY CASE REPORTS | 2013年 / 7卷 / 03期

关键词：

Cerebral autosomal dominant arteriopathy with subcortical infracts and leukoencephalopathy; CADASIL; Watershed infarcts; Global cerebral hypoperfusion; MRI;

D O I：

10.3941/jrcr.v7i3.1312

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common form of hereditary cerebral angiopathy. We present a case in which a pattern of diffusion signal change compatible with bihemispheric acute watershed infarcts occurred in a symptomatic patient demonstrating global hypoperfusion. To our knowledge, watershed infarcts in the clinical presentation of CADASIL have not been previously described.

引用

页码：8 / 15

页数：8

共 14 条

[1]

Bruening R, 2001, AM J NEURORADIOL, V22, P1268

[2] Cerebral hemodynamics in CADASIL before and after acetazolamide challenge assessed with MRI bolus tracking [J].

Chabriat, H ;

Pappata, S ;

Ostergaard, L ;

Clark, CA ;

Pachot-Clouard, M ;

Vahedi, K ;

Jobert, A ;

Le Bihan, D ;

Bousser, MG .

STROKE, 2000, 31 (08) :1904-1912

[3] CADASIL [J].

Chabriat, Hugues ;

Joutel, Anne ;

Dichgans, Martin ;

Tournier-Lasserve, Elizabeth ;

Bousser, Marie-Germaine .

LANCET NEUROLOGY, 2009, 8 (07) :643-653

[4] Severe hemodynamic impairment and border zone-region infarction [J].

Derdeyn, CP ;

Khosla, A ;

Videen, TO ;

Fritsch, SM ;

Carpenter, DL ;

Grubb, RL ;

Powers, WJ .

RADIOLOGY, 2001, 220 (01) :195-201

[5] Cognitive impairment of vascular origin: Neuropathology of cognitive impairment of vascular origin [J].

Ferrer, Isidre .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 2010, 299 (1-2) :139-149

[6] Acetazolamide improves cerebral hemodynamics in CADASIL [J].

Huang, Li ;

Yang, Qidong ;

Zhang, Le ;

Chen, Xuan ;

Huang, Qing ;

Wang, Hongxing .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 2010, 292 (1-2) :77-80

[7] Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease [J].

Joutel, Anne ;

Monet-Lepretre, Marie ;

Gosele, Claudia ;

Baron-Menguy, Celine ;

Hammes, Annette ;

Schmidt, Sabine ;

Lemaire-Carrette, Barbara ;

Domenga, Valerie ;

Schedl, Andreas ;

Lacombe, Pierre ;

Hubner, Norbert .

JOURNAL OF CLINICAL INVESTIGATION, 2010, 120 (02) :433-445

[8] Impaired cerebral vasoreactivity in a transgenic mouse model of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy arteriopathy [J].

Lacombe, P ;

Oligo, C ;

Domenga, V ;

Tournier-Lasserve, E ;

Joutel, A .

STROKE, 2005, 36 (05) :1053-1058

[9] Prolonged cerebral transit time in CADASIL - A transcranial ultrasound study [J].

Liebetrau, M ;

Herzog, J ;

Kloss, CUA ;

Hamann, GF ;

Dichgans, M .

STROKE, 2002, 33 (02) :509-512

[10] MRI correlates of cognitive decline in CADASIL A 7-year follow-up study [J].

Liem, M. K. ;

Oberstein, S. A. J. Lesnik ;

Haan, J. ;

Van der Neut, I. L. ;

Ferrari, M. D. ;

Van Buchem, M. A. ;

Middelkoop, H. A. M. ;

Van der Grond, J. .

NEUROLOGY, 2009, 72 (02) :143-148

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