NAD-LINKED GLUTAMATE-DEHYDROGENASE IN TRYPANOSOMA-CRUZI

被引：21

作者：

CAZZULO, JJ

FRANKEDECAZZULO, BM

HIGA, AI

SEGURA, EL

机构：

[1] NATL UNIV ROSARIO,CONICET FDN MIGUEL LILLO,ROSARIO 2000,ARGENTINA

[2] INST NACL DIAGNOST & INVEST ENFERMEDAD CHAGAS DR MARIO FATALA CHABEN,BUENUS AIRES 1063,ARGENTINA

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1979年 / 64卷 / 01期

关键词：

D O I：

10.1016/0305-0491(79)90197-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. 1. Epimastigotes of Trypanosoma cruzi, Tulahuén strain, contained a NAD-linked glutamate dehydrogenase (EC 1.4.1.3), in addition to the already known NADP-linked enzyme (EC 1.4.1.4). 2. 2. The partially purified NAD-linked enzyme had a higher molecular weight and was much more labile than the NADP-linked enzyme, and was inhibited by purine nucleotides. 3. 3. These results further emphasize the difference in glutamate metabolism between the parasite and its mammalian host. © 1979.

引用

页码：129 / 131

页数：3

共 9 条

[1] REGULATION OF ENZYME FUNCTION [J].

ATKINSON, DE .

ANNUAL REVIEW OF MICROBIOLOGY, 1969, 23 :47-+

[2]

Cataldi de Flombaum M. A, 1977, Comparative Biochem Physiol (B), V58, P67, DOI 10.1016/0305-0491(77)90129-8

[3] GLUTAMATE-DEHYDROGENASE AND ASPARTATE-AMINOTRANSFERASE IN TRYPANOSOMA-CRUZI [J].

CAZZULO, JJ ;

JUAN, SM ;

SEGURA, EL .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 1977, 56 (03) :301-303

[4]

FRASCH ACC, 1978, COMP BIOCHEM PHYS B, V61, P207, DOI 10.1016/0305-0491(78)90162-1

[5] PURIFICATION AND SOME PROPERTIES OF NADP-LINKED GLUTAMATE-DEHYDROGENASE FROM TRYPANOSOMA-CRUZI [J].

JUAN, SM ;

SEGURA, EL ;

CAZZULO, JJ .

INTERNATIONAL JOURNAL OF BIOCHEMISTRY, 1978, 9 (06) :395-+

[6]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

[7] ANTIGENIC MAKEUP OF SUBCELLULAR-FRACTIONS OF TRYPANOSOMA-CRUZI [J].

SEGURA, EL ;

CURA, EN ;

PAULONE, I ;

VASQUEZ, C ;

CERISOLA, JA .

JOURNAL OF PROTOZOOLOGY, 1974, 21 (04) :571-574

[8]

Smith E. I., 1975, ENZYMES, VXI, P294

[9]

Warburg O., 1941, BIOCHEM Z, V310, P384

← 1 →