FULMINANT HEPATIC-FAILURE AFTER METHOTREXATE AND PUVA THERAPY FOR PSORIASIS

被引：8

作者：

MARKIN, RS

DONOVAN, JP

SHAW, BW

ZETTERMAN, RK

机构：

[1] UNIV NEBRASKA,MED CTR,DEPT INTERNAL MED,OMAHA,NE 68105

[2] UNIV NEBRASKA,MED CTR,DEPT SURG,OMAHA,NE 68105

来源：

JOURNAL OF CLINICAL GASTROENTEROLOGY | 1993年 / 17卷 / 04期

关键词：

PSORIASIS; METHOTREXATE; PUVA THERAPY; FULMINANT HEPATIC FAILURE;

D O I：

10.1097/00004836-199312000-00010

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Acute hepatic failure developed after 8-methoxypsoralen and ultraviolet irradiation for psoriasis in a patient with prior methotrexate-induced cirrhosis. Review of the literature and the temporal relationship between 8-methoxypsoralen and hepatic injury in our patient suggests it may be a direct hepatotoxin. In our report, submassive necrosis superimposed on cirrhosis appears to have produced hepatic failure.

引用

页码：311 / 313

页数：3

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