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FULMINANT HEPATIC-FAILURE AFTER METHOTREXATE AND PUVA THERAPY FOR PSORIASIS
被引：8
|作者：
MARKIN, RS
DONOVAN, JP
SHAW, BW
ZETTERMAN, RK
机构：
[1] UNIV NEBRASKA,MED CTR,DEPT INTERNAL MED,OMAHA,NE 68105
[2] UNIV NEBRASKA,MED CTR,DEPT SURG,OMAHA,NE 68105
关键词：
PSORIASIS;
METHOTREXATE;
PUVA THERAPY;
FULMINANT HEPATIC FAILURE;
D O I：
10.1097/00004836-199312000-00010
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Acute hepatic failure developed after 8-methoxypsoralen and ultraviolet irradiation for psoriasis in a patient with prior methotrexate-induced cirrhosis. Review of the literature and the temporal relationship between 8-methoxypsoralen and hepatic injury in our patient suggests it may be a direct hepatotoxin. In our report, submassive necrosis superimposed on cirrhosis appears to have produced hepatic failure.
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页码：311 / 313
页数：3
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