PETHIDINE HAS A LOCAL-ANESTHETIC ACTION ON PERIPHERAL-NERVES INVIVO - ADDITION TO PRILOCAINE 0.25-PERCENT FOR INTRAVENOUS REGIONAL ANESTHESIA IN VOLUNTEERS

被引：51

作者：

ARMSTRONG, PJ

MORTON, CPJ

NIMMO, AF

机构：

[1] Department of Anaesthetics, University of Edinburgh, Royal Infirmary, Edinburgh, EH3 9YW, Lauriston Place

来源：

ANAESTHESIA | 1993年 / 48卷 / 05期

关键词：

ANESTHETICS; LOCAL; PRILOCAINE; ANALGESICS; PETHIDINE; ANESTHETIC TECHNIQUES; REGIONAL; INTRAVENOUS;

D O I：

10.1111/j.1365-2044.1993.tb07008.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

In a double‐blind, randomised study, we have examined the effects of the addition of pethidine 100 mg to 40 ml prilocaine 0.25% for intravenous regional anaesthesia in healthy volunteers. During intravenous regional anaesthesia the hand and forearm are isolated from the rest of the circulation and pethidine interaction with central opiate receptors does not occur. Pethidine increased the speed of onset and extent of sensory and motor block, reduced tourniquet and forearm pain, and subjectively improved the quality of the block. Pethidine has local anaesthetic action on peripheral nerves in vivo. Copyright © 1993, Wiley Blackwell. All rights reserved

引用

页码：382 / 386

页数：5