THE POTENTIAL CARCINOGENIC EFFECT OF UVINUL-DS49 - A COMMON UV ABSORBER USED IN COSMETICS

被引：9
作者：
BOLTON, K
MARTINCIGH, BS
SALTER, LF
机构：
[1] University of Natal, Department of Chemistry and Applied Chemistry, Durban, 4001, King George V Ave
来源：
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY | 1992年 / 63卷 / 02期
关键词：
D O I：
10.1016/1010-6030(92)85142-H
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The photosensitized production of thymine dimer at 324 nm was investigated using disodium-2, 2'-dihydroxy-4,4'-dimethoxybenzophenone sulphonic acid (tradename, Uvinul DS49) as sensitizer. Yields of the dimer for various irradiation times, initial thymine concentrations and initial sensitizer concentrations were determined for the free thymine base in aqueous medium. A reaction mechanism is proposed for total thymine dimer formation together with the corresponding rate constants. The mechanism and rate constants were computer simulated to support their validity.
引用
收藏
页码：241 / 248
页数：8
相关论文
共 17 条
[1]   BENZOPHENONE TRIPLET PROPERTIES IN ACETONITRILE AND WATER - REDUCTION BY LACTAMS [J].
BENSASSON, RV ;
GRAMAIN, JC .
JOURNAL OF THE CHEMICAL SOCIETY-FARADAY TRANSACTIONS I, 1980, 76 :1801-1810
[2]   ISOLATION AND IDENTIFICATION OF THE IRRADIATION PRODUCT OF THYMINE [J].
BEUKERS, R ;
BERENDS, W .
BIOCHIMICA ET BIOPHYSICA ACTA, 1960, 41 (03) :550-551
[3]  
Cadet J, 1990, BIOORGANIC PHOTOCHEM, V1, P1
[4]   PHOTOCHEMICAL REACTIONS OF AROMATIC KETONES WITH NUCLEIC-ACIDS AND THEIR COMPONENTS .1. PURINE AND PYRIMIDINE BASES AND NUCLEOSIDES [J].
CHARLIER, M ;
HELENE, C .
PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1972, 15 (01) :71-&
[5]   REACTION SELECTIVITY AND MOLECULAR ASSOCIATION IN PHOTOCHEMICAL REACTIONS OF NUCLEIC-ACIDS AND THEIR CONSTITUENTS [J].
ELAD, D .
PURE AND APPLIED CHEMISTRY, 1977, 49 (04) :503-509
[6]   A NEW SENSITIVE CHEMICAL ACTINOMETER .2. POTASSIUM FERRIOXALATE AS A STANDARD CHEMICAL ACTINOMETER [J].
HATCHARD, CG ;
PARKER, CA .
PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES A-MATHEMATICAL AND PHYSICAL SCIENCES, 1956, 235 (1203) :518-536
[7]   THE KINETICS OF PHOTOSENSITIZED THYMINE DIMERIZATION [J].
KILFOIL, V ;
SALTER, L .
INTERNATIONAL JOURNAL OF CHEMICAL KINETICS, 1988, 20 (08) :645-659
[8]  
LEDGER MB, 1971, T FARADAY SOC, V67, P539
[9]   UV ABSORBERS IN SUN COSMETICS 1978 [J].
LIEM, DH ;
HILDERINK, LTH .
INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, 1979, 1 (06) :341-361
[10]  
LIN SH, 1975, PHYSICAL CHEM ADV TR, V7, P18
12