This study was conducted to find out the effect of combined application of fluorescent Pseudomonas, spent mushroom compost and the fungicide (Carbendazim 50 % W.P) on Fusarium wilt disease infected tomato plants grown in solarized and non-solarized soil. Results of study revealed that inoculation of fluorescent Pseudomonas and spent mushroom compost have significant effect on the number and weight of tomato fruits per replicate with cost benefit ratio as compared to the control treatment having Fusarium oxysporum f.sp. lycopersici infection. No significance differences was reported among the various treatments imposed, and highest tomato fruit per plant (8.75 fruits/plant) was reported from the treatment containing only sterilized soil after 150 days of plantation this was followed by treatment containing P. fluorescens (7.35 fruits/plant), spent mushroom compost (7.00 fruits/plant), Carbendazim (7.00 fruits/plant) and spent mushroom compost with Pseudomonas fluorescens (6.90 tomato fruit/plant). Similar trends was reported in case of fruit weight and net return and treatment containing only sterilized soil show highest fruit weight (158.60g), maximum net return (113329 Rs/ha) and incremental cost benefit ratio (1:4.50). While minimum net return (0 Rs/ha) was observed in the treatment containing non sterilized soil and F. oxysporum infection.