THYROID-HORMONES AND ATRIAL NATRIURETIC HORMONE-SECRETION - STUDY IN HYPERTHYROID AND HYPOTHYROID PATIENTS

被引：11

作者：

ROLANDI, E ^{[1
]}

SANTANIELLO, B ^{[1
]}

BAGNASCO, M ^{[1
]}

CATALDI, A ^{[1
]}

GARIBALDI, C ^{[1
]}

FRANCESCHINI, R ^{[1
]}

BARRECA, T ^{[1
]}

机构：

[1] UNIV GENOA,DEPT INTERNAL MED,I-16126 GENOA,ITALY

来源：

ACTA ENDOCRINOLOGICA | 1992年 / 127卷 / 01期

关键词：

D O I：

10.1530/acta.0.1270023

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Plasma atrial natriuretic hormone (ANH) values were evaluated in 28 hyperthyroid patients and in 11 hypothyroid patients and compared with 20 healthy subjects. In hyperthyroid patients plasma ANH basal levels were significantly (p < 0.01) higher (14.2 +/- 1.6 pmol/l) than in controls (7.8 +/- 0.4 pmol/l) and in hypothyroid patients (6.4 +/- 0.3 pmol/l). No significant differences were found between controls and hypothyroid patients. The propranolol-induced decrease in heart rate in hyperthyroid patients did not significantly affect the plasma ANH values. Conversely, after the methimazole-induced euthyroidism a return within the normal range of ANH values was observed. The thyroxine replacement in hypothyroid patients determined a small but significant (p < 0.05) increase in plasma ANH values. Observed data suggest that in humans thyroid hormones may influence plasma ANH concentrations independently of their effect on heart rate.

引用

页码：23 / 26

页数：4

共 20 条

[1] HUMAN ATRIAL-NATRIURETIC-PEPTIDE [J].