ISOLATION AND CHARACTERIZATION OF 2 NOVEL NEMATOCIDAL DEPSIPEPTIDES FROM AN IMPERFECT FUNGUS, STRAIN D1084

被引：24

作者：

KAWAZU, K ^{[1
]}

MURAKAMI, T ^{[1
]}

ONO, Y ^{[1
]}

KANZAKI, H ^{[1
]}

KOBAYASHI, A ^{[1
]}

MIKAWA, T ^{[1
]}

YOSHIKAWA, N ^{[1
]}

机构：

[1] MITSUBISHI KASEI LTD, RES CTR, YOKOHAMA 227, JAPAN

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1993年 / 57卷 / 01期

关键词：

D O I：

10.1271/bbb.57.98

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two novel nematicidal cyclodepsipeptides, designated bursaphelocides A and B, were isolated from the culture filtrate of an imperfect fungus, strain D1084, belonging to Mycelia sterilia. Bursaphelocide A (1), containing 2-hydroxy-3-methylpentanoic acid, proline, isoleucine, N-methylalanine, N-methylvaline, and beta-alanine in sequence, and bursaphelocide B (2), comprising 4-methylproline instead of proline in 1, are novel 2-hydroxy-3-methylpentanoic acid analogues of insecticidal destruxins.

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页码：98 / 101

页数：4

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