Perieccrine and pericapillary calcification in calciphylaxis

被引:4
作者
Dookhan, Christina [1 ]
Ortega, Luis M. [2 ]
Nayer, Ali [3 ]
Cho-Vega, Jeong Hee [4 ]
机构
[1] Univ Miami, Miller Sch Med, Dept Internal Med, Miami, FL 33136 USA
[2] Temple Univ, Sch Med, Allegheny Gen Hosp, Div Nephrol & Hypertens, Pittsburgh, PA USA
[3] Univ Miami, Miller Sch Med, Div Nephrol & Hypertens, Miami, FL 33136 USA
[4] Univ Miami, Miller Sch Med, Dermatopathol Div, Dept Pathol, Miami, FL 33136 USA
关键词
Calciphylaxis; Perieccrine calcification; Pericapillary calcification;
D O I
10.12861/jrip.2015.03
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Implication for health policy/practice/research/medical education Calciphylaxis, also known as calcific uremic arteriolopathy, is characterized by ischemic tissue necrosis secondary to an obliterative vasculopathy. On histological examination, small and medium-sized arteries demonstrate medial calcification, intimal hyperplasia and thrombosis. However, vascular pathology may not be evident when small skin biopsies are examined. Subtle stippled perieccrine calcification revealed by calcium staining (von Kossa) is highly specific for calciphylaxis and can aid in the histological diagnosis of calciphylaxis when vascular calcification is not evident on small skin biopsies.
引用
收藏
页码:9 / 10
页数:2
相关论文
共 3 条
[1]   Cutaneous Calciphylaxis: A Retrospective Histopathologic Evaluation [J].
Mochel, Mark C. ;
Arakaki, Ryan Y. ;
Wang, Guilin ;
Kroshinsky, Daniela ;
Hoang, Mai P. .
AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2013, 35 (05) :582-586
[2]   Calciphylaxis [J].
Nayer, Ali ;
Salman, Loay ;
Asif, Arif .
CLINICAL KIDNEY JOURNAL, 2013, 6 (06) :653-654
[3]  
Nayer A, 2014, IRAN J KIDNEY DIS, V8, P252