Lead Nitrate Induced Oxidative Stress in Brain Tissues of Rats: Protective Effect of Sodium Selenite

被引：0

作者：

Kalender, Suna ^{[1
]}

Apaydin, Fatma Gokce ^{[2
]}

Demir, Filiz ^{[3
]}

Bas, Hatice ^{[4
]}

机构：

[1] Gazi Univ, Gazi Educ Fac, Dept Sci Educ, Ankara, Turkey

[2] Gazi Univ, Fac Sci, Dept Biol, Ankara, Turkey

[3] Gaziosmanpasa Univ, Grad Sch Nat & Appl Sci, Tokat, Turkey

[4] Bozok Univ, Fac Arts & Sci, Dept Biol, Yozgat, Turkey

来源：

GAZI UNIVERSITY JOURNAL OF SCIENCE | 2014年 / 27卷 / 03期

关键词：

Lead Nitrate; Sodium selenite; Antioxidant Enzymes; Oxidative stress; Brain;

D O I：

暂无

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Lead used in many industrial applications and it has been recognized as a toxic metal. The aim of this study is to investigate the effects of lead nitrate on brain tissues of diabetic and non-diabetic rats and the protective role of sodium selenite. Four weeks later, changes in antioxidant enzyme activities and MDA levels determined in the brain tissues. At the end of the study, we showed that lead nitrate causes oxidative stress in diabetic and non-diabetic rat brain and the sodium selenite can ameliorate this toxicity, but not protect completely.

引用

页码：883 / 889

页数：7

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