Endotoxin removal by membrane affinity chromatography

被引：0
|
作者：
Guo, W
Shang, ZH
Yu, YN
Zhou, LM
Zun, ZY
Ma, LR
Chen, MY
机构：
[1] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116012, Peoples R China
[2] Acad Mil Med Sci, Inst Radiat Med, Beijing 100850, Peoples R China
来源：
CHINESE CHEMICAL LETTERS | 1995年 / 6卷 / 10期
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Endotoxin was removed by membrane affinity chromatography. Macropore cellulose membrane was prepared from filter paper by alkaline treatment and chemical crosslinking, and was used as stationary phase for affinity chromatography. The matrix membrane was derived by hexamethylenediamine and activated by glutaraldehyde before histidine was immobilized as affinity ligand. A membrane cartridge containing 40 sheets of affinity membrane was also prepared, which can be used to remove pyrogen from aqueous solutions.
引用
收藏
页码：919 / 922
页数：4
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