DIFFERENT STRESSORS AND BLOOD LIPID-PEROXIDATION

被引：0

作者：

LAVICKY, J

RASKOVA, H

机构：

[1] CZECHOSLOVAK ACAD SCI, CS-11142 PRAGUE 1, CZECHOSLOVAKIA

[2] CHARLES UNIV, FAC MED 2, INST PHARMACOL, CS-11636 PRAGUE 1, CZECHOSLOVAKIA

来源：

ARZNEIMITTELFORSCHUNG-DRUG RESEARCH | 1991年 / 41-2卷 / 08期

关键词：

ENDOTOXINS; LIPID PEROXIDATION; EFFECT OF STRESSORS; LIPOPOLYSACCHARIDE; PHARMACOLOGY; PEPTIDOGLYCAN; STRESSORS; VIBRATION;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Elevation of lipid peroxidation (LOX) was observed in rabbits and mice after the intravenous administration of 0.2-mu-g . kg-1 of lipopolysaccharide (LPS) and 100-mu-g . kg-1 of peptidoglycan (MP). The peak was reached sooner after peptidoglycan, and 2-4 h after LPS administration. The trends of lipid peroxidation were the same in both species. 8-10 h later original LOX blood levels were reached. Mild horizontal vibration (1 h) induced in both species a significant lowering of LOX. This appeared already immediately after the vibration. Original values were gained again after 8-10 h. The difference between the internal stressors, LPS and MP, and the external stressor, vibration, are discussed.

引用

页码：793 / 796

页数：4

共 18 条

[1]

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[2]

BLATTEIS C, 1990, 1ST C INT END SOC

[3]

BOSCH MA, 1990, 1ST INT C INT END SO, P52

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