PUROMYCIN - EFFECT ON MEMORY OF MICE WHEN INJECTED WITH VARIOUS CATIONS

被引：12

作者：

FLEXNER, JB

FLEXNER, LB

机构：

来源：

SCIENCE | 1969年 / 165卷 / 3898期

关键词：

D O I：

10.1126/science.165.3898.1143

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Puromycin dihydrochloride neutralized with bases of potassium, lithium, calcium, or magnesium fails to block expression of memory of maze learning in mice, unlike puromycin neutralized with NaOH. This failure may be due to cationic binding at anionic membrane sites with a resultant exclusion of sufficient peptidyl-puromycin to make it ineffective in blocking memory.

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页码：1143 / &

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