UNCONVENTIONAL NUCLEOTIDE ANALOGUES .2. SYNTHESIS OF ADENYL ANALOGUE OF WILLARDIINE

被引：27
作者：
NOLLET, AJH
PANDIT, UK
机构：
[1] Laboratory of Organic Chemistry, University of Amsterdam, Amsterdam
来源：
TETRAHEDRON | 1969年 / 25卷 / 24期
关键词：
D O I：
10.1016/S0040-4020(01)83105-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The Michael addition of adenine (6a), 6-chloropurine (6b) and 2,6-dichloropurine (6c) to methyl α-chloroacrylate gives high yields of the corresponding adducts (7a-7c). Hydrolysis and amination of 7a gave the adenyl analogue of Willardiine (2). © 1969.
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页码：5983 / &
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