Serum level of vitamin D3 in cutaneous melanoma

被引:6
作者
de Oliveira Filho, Renato Santos [1 ]
de Oliveira, Daniel Arcuschin [1 ]
Melao Martinho, Vitor Augusto [1 ]
Gianotti Antoneli, Celia Beatriz [1 ]
de Lima Marcussi, Ludmilla Altino [1 ]
dos Santos Ferreira, Carlos Eduardo [1 ]
机构
[1] Hosp Israelita Albert Einstein, Ave Reboucas,2.849 Cerqueira Cesar, BR-05401350 Sao Paulo, SP, Brazil
来源
EINSTEIN-SAO PAULO | 2014年 / 12卷 / 04期
关键词
Calcifediol; Cholecalciferol; Receptors; calcitriol; Vitamin D deficiency; Melanoma; Immune system;
D O I
10.1590/S1679-45082014AO3090
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To compare the level of vitamin D3 in cutaneous melanoma patients, with or without disease activity, with reference values and with patients from a general hospital. Methods: The serum levels of vitamin D3 were measured in cutaneous melanoma patients, aged 20 to 88 years, both genders, from January 2010 to December 2013. The samples from the general group were processed at Hospital Israelita Albert Einstein (control group). Data analysis was performed using the Statistics software. Results: A total of 100 patients were studied, 54 of them men, with mean age of 54.67 years, and 95 Caucasian. Out of these 100 patients, 17 had active disease. The average levels of vitamin D3 in the melanoma patients were lower than the level considered sufficient, but above the average of the control group. Both groups (with or without active disease) of patients showed a similar distribution of vitamin D3 deficiency. Conclusion: Vitamin D3 levels in melanoma patients were higher than those of general patients and lower than the reference level. If the reference values are appropriate, a large part of the population had insufficient levels of vitamin D, including those with melanoma, or else, this standard needs to be reevaluated. No difference in vitamin D3 levels was found among melanoma patients with or without active disease. More comprehensive research is needed to assess the relation between vitamin D and melanoma.
引用
收藏
页码:473 / 476
页数:4
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