EFFECT OF NERVE STIMULATION ON UPTAKE OF NORADRENALINE INTO ADRENERGIC NERVE TERMINALS

被引:23
作者
HAGGENDAL, J
MALMFORS, T
机构
[1] Department of Pharmacology, University of Göteborg
[2] Department of Histology, Karolinska Institutet, Stockholm
来源
ACTA PHYSIOLOGICA SCANDINAVICA | 1969年 / 75卷 / 1-2期
关键词
D O I
10.1111/j.1748-1716.1969.tb04351.x
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
In rats pretreated with reserpine and nialamide the effect of sympathetic stimulation, 20 and 6 imp/sec, on the uptake of exogenous noradrenaline was studied in the adrenergic nerves of the iris and salivary glands using fluorescence and biochemical methods, respectively. The uptake of noradrenaline was smaller on the stimulated than on the unstimulated side. The results are discussed with respect to factors such as changes in the circulation, transmitter release during the stimulation, and the presence of an intermittent blockade of the membrane pump during the impulses. It is suggested that the latter mechanisms might be of some physiological importance. © 1969 Scandinavian Physiological Society
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页码:28 / +
页数:1
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