ANALYSIS OF CROSS-REACTIVITY BETWEEN SUNFLOWER POLLEN AND OTHER POLLENS OF THE COMPOSITAE FAMILY

被引：56

作者：

FERNANDEZ, C ^{[1
]}

MARTINESTEBAN, M ^{[1
]}

FIANDOR, A ^{[1
]}

PASCUAL, C ^{[1
]}

SERRANO, CL ^{[1
]}

ALZAMORA, FM ^{[1
]}

PENA, JMD ^{[1
]}

CASAS, JAO ^{[1
]}

机构：

[1] HOSP LA PAZ,MADRID,SPAIN

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 1993年 / 92卷 / 05期

关键词：

HAY FEVER; POLLEN ALLERGENS; ENTOMOPHILOUS POLLEN; SUNFLOWER ALLERGY; COMPOSITAE POLLEN; CROSS-REACTIVITY;

D O I：

10.1016/0091-6749(93)90008-4

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The sera of 20 patients with Compositae pollen allergy were investigated for the presence of IgE antibodies reacting against sunflower pollen by means of RAST and immmunoblotting studies. Thirteen IgE-binding bands were detected with molecular weights ranging from 14.4 to 94 kd. Two of these bands, with molecular weights of 24 and 25 kd, contained major allergens that reacted strongly with 100% (24 kd) and 95% (25 kd) of the sera, respectively. Cross-reactivity between sunflower and other Compositae pollens (mugwort, marguerite, dandelion, golden rod, and short ragweed) was revealed by RAST and immunoblotting inhibition experiments. Mugwort pollen exhibited the greatest degree of allergenic homology (cross-reactivity) with sunflower pollen, whereas at the other end of the spectrum, short ragweed showed less cross-reactive epitopes.

引用

页码：660 / 667

页数：8

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