IDENTIFICATION OF THE GLYCOSYLATED SEQUONS OF HUMAN MYELIN-ASSOCIATED GLYCOPROTEIN

被引：17

作者：

BURGER, D ^{[1
]}

PIDOUX, L ^{[1
]}

STECK, AJ ^{[1
]}

机构：

[1] CHU VAUDOIS, DEPT NEUROL, NEUROBIOL LAB, LAUSANNE, SWITZERLAND

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1993年 / 197卷 / 02期

关键词：

D O I：

10.1006/bbrc.1993.2501

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Myelin-associated glycoprotein (MAG) is a neural cell adhesion molecule expressing the L2/HNK-1 carbohydrate epitope. MAG is heavily glycosylated containing 30% carbohydrate by weight. In this study, human MAG glycopeptides were isolated and sequenced. Of the 9 MAG sequons 7 were glycosylated and 1 was partially glycosylated at Asn106. Asn332 which was not recovered in the glycopeptide fractions was probably not glycosylated. Furthermore, preliminary data indicate that all MAG glycosylated sequons might bear the L2/HNK-1 epitope. © 1993 Academic Press, Inc.

引用

页码：457 / 464

页数：8

共 50 条

[21] GANGLIOSIDES ARE NEURONAL LIGANDS FOR MYELIN-ASSOCIATED GLYCOPROTEIN
YANG, LJS
ZELLER, CB
SHAPER, NL
KISO, M
HASEGAWA, A
SHAPIRO, RE
SCHNAAR, RL
MOLECULAR BIOLOGY OF THE CELL, 1995, 6 : 1902 - 1902
[22] Organization of myelin protein genes. Myelin-associated glycoprotein
Milner, Robert J.
Lai, Cary
Nave, Klaus-Armin
Montag, Dirk
Farber, Len
Sutcliffe, J. Gregor
Annals of the New York Academy of Sciences, 1990, 605
[23] PREPARATION AND CHARACTERIZATION OF ANTISERA TO THE MYELIN-ASSOCIATED GLYCOPROTEIN
QUARLES, RH
JOHNSON, D
BRADY, RO
STERNBERGER, NH
NEUROCHEMICAL RESEARCH, 1981, 6 (10) : 1115 - 1127
[24] ABNORMALITIES OF MYELIN-ASSOCIATED GLYCOPROTEIN IN QUAKING MUTANTS
QUARLES, R
BARTOSZEWICZ, Z
NORONHA, A
BO, L
TRAPP, B
FUJITA, N
SATO, S
JOURNAL OF NEUROCHEMISTRY, 1994, 62 : S54 - S54
[25] Entrapment in anti myelin-associated glycoprotein neuropathy
Catharina G. Faber
Nicolette C. Notermans
John H. J. Wokke
Hessel Franssen
Journal of Neurology, 2009, 256 : 620 - 624
[26] MYELIN-ASSOCIATED GLYCOPROTEIN SHARES AN ANTIGENIC DETERMINANT WITH A GLYCOPROTEIN OF HUMAN-MELANOMA CELLS
NORONHA, AB
HARPER, JR
ILYAS, AA
REISFELD, RA
QUARLES, RH
JOURNAL OF NEUROCHEMISTRY, 1986, 47 (05) : 1558 - 1565
[27] PHOSPHORYLATION OF MYELIN-ASSOCIATED GLYCOPROTEIN IN CULTURED OLIGODENDROCYTES
BAMBRICK, LL
BRAUN, PE
DEVELOPMENTAL NEUROSCIENCE, 1991, 13 (06) : 412 - 416
[28] Axonal Protective Effects of the Myelin-Associated Glycoprotein
Nguyen, Thien
Mehta, Niraj R.
Conant, Katherine
Kim, Kee-Jun
Jones, Melina
Calabresi, Peter A.
Melli, Giorgia
Hoke, Ahmet
Schnaar, Ronald L.
Ming, Guo-Li
Song, Hongjun
Keswani, Sanjay C.
Griffin, John W.
JOURNAL OF NEUROSCIENCE, 2009, 29 (03): : 630 - 637
[29] CHARACTERIZATION OF THE MYELIN-ASSOCIATED GLYCOPROTEIN RECEPTOR ON NEURONS
DEBELLARD, M
TANG, S
FILBIN, MT
JOURNAL OF NEUROCHEMISTRY, 1995, 65 : S112 - S112
[30] Gangliosides are neuronal ligands for myelin-associated glycoprotein
Yang, L. J.-S.
Zeller, C. B.
Shaper, N. L.
Kiso, M.
Physical Review B: Condensed Matter, 53 (11):

← 1 2 3 4 5 →