ISOLATION OF 2 HEMORRHAGIC TOXINS FROM CROTALUS-BASILISCUS BASILISCUS (MEXICAN WEST-COAST RATTLESNAKE) VENOM AND THEIR EFFECT ON BLOOD-CLOTTING AND COMPLEMENT

被引：16

作者：

MOLINA, O

SERIEL, RK

MARTINEZ, M

SIERRA, ML

VARELARAMIREZ, A

RAEL, ED

机构：

来源：

INTERNATIONAL JOURNAL OF BIOCHEMISTRY | 1990年 / 22卷 / 03期

关键词：

D O I：

10.1016/0020-711X(90)90337-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. 1. Two hemorrhagic toxins of mol. wt 27,000 (Bl) and 27.500 (B2) and pi 9.8 and 5.2 respectively were isolated from Crotalus basiliscus venom. 2. 2. The two proteinases did not cross-react antigenically. 3. 3. Both toxins caused hemorrhage in mice and each was capable of hydrolyzing hide powder azure, casein, collagen and fibrin. 4. 4. Bl hydrolyzed the Aga, Bgb and gg chains of fibrinogen. B2 hydrolyzed the Aa and Bgb chains of fibrinogen, but not the gg chain. 5. 5. Both proteinases inactivated guinea pig complement. © 1990.

引用

页码：253 / &

共 3 条

[1] ISOLATION OF A TOXIN FROM THE VENOM OF THE MEXICAN WEST-COAST RATTLESNAKE (CROTALUS-BASILISCUS) WITH ANTI-MOJAVE TOXIN ANTIBODIES
REYES, LA
RAEL, ED
TOXICON, 1987, 25 (02) : 153 - 153
[2] PURIFICATION AND CHARACTERIZATION OF 3 ALPHA-2-ANTIPLASMIN AND ALPHA-2-MACROGLOBULIN INACTIVATING ENZYMES FROM THE VENOM OF THE MEXICAN WEST-COAST RATTLESNAKE (CROTALUS-BASILISCUS)
SVOBODA, P
MEIER, J
FREYVOGEL, TA
TOXICON, 1995, 33 (10) : 1331 - 1346
[3] Proteomic, toxicological and immunogenic characterization of Mexican west -coast rattlesnake (Crotalus basiliscus) venom and its immunological relatedness with the venom of Central American rattlesnake (Crotalus simus)
Segura, Alvaro
Herrera, Maria
Reta Mares, Francisco
Jaime, Claudia
Sanchez, Andres
Vargas, Mariangela
Villalta, Mauren
Gomez, Aaron
Maria Gutierrez, Jose
Leon, Guillermo
JOURNAL OF PROTEOMICS, 2017, 158 : 62 - 72

← 1 →